HAO1 Protein (AA 1-370) (His tag)
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- Target See all HAO1 Proteins
- HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-370
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HAO1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HAO1, 1-370aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HAO1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.5M NaCl
- Storage
- 4 °C
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- Target
- HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
- Alternative Name
- HAO1 (HAO1 Products)
- Synonyms
- hao1 Protein, GOX Protein, GOX1 Protein, HAOX1 Protein, Gox1 Protein, XDH1 Protein, Hao-1 Protein, hydroxyacid oxidase 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog Protein, hydroxyacid oxidase 1, liver Protein, CpipJ_CPIJ013711 Protein, THEYE_A0075 Protein, hao1 Protein, HAO1 Protein, hao1.L Protein, Hao1 Protein
- Background
- HAO1, also known as glycolate oxidase, is a member of the superfamily of the alpha hydroxy acid oxidases(HAO) enzymes. It catalyzes the FMN mediated oxidation of glycolate to glyoxylate and glyoxylate to oxalate with reduction of oxygen to hydrogen peroxide. It is most highly expressed in liver and pancreas and is most active on twocarbon substrates such as glycolate. Recently, it has been identified as a major contributor to hyperoxaluria, a disorder in which large deposits of calcium oxalate form kidney stones. Recombinant human HAO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Hydroxyacid oxidase 1, GOX (glycolate oxidase), GOX1, HAOX1. NCBI no.: NP_060015
- Molecular Weight
- 45.0 kDa(406aa), confirmed by MALDI-TOF
- Pathways
- Monocarboxylic Acid Catabolic Process
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