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HAO1 Protein (AA 1-370) (His tag)

HAO1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667522
  • Target See all HAO1 Proteins
    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-370
    Origin
    • 6
    • 4
    • 3
    • 1
    Human
    Source
    • 9
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HAO1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    HAO1, 1-370aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HAO1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.5M NaCl
    Storage
    4 °C
  • Target
    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
    Alternative Name
    HAO1 (HAO1 Products)
    Synonyms
    hao1 Protein, GOX Protein, GOX1 Protein, HAOX1 Protein, Gox1 Protein, XDH1 Protein, Hao-1 Protein, hydroxyacid oxidase 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog Protein, hydroxyacid oxidase 1, liver Protein, CpipJ_CPIJ013711 Protein, THEYE_A0075 Protein, hao1 Protein, HAO1 Protein, hao1.L Protein, Hao1 Protein
    Background
    HAO1, also known as glycolate oxidase, is a member of the superfamily of the alpha hydroxy acid oxidases(HAO) enzymes. It catalyzes the FMN mediated oxidation of glycolate to glyoxylate and glyoxylate to oxalate with reduction of oxygen to hydrogen peroxide. It is most highly expressed in liver and pancreas and is most active on twocarbon substrates such as glycolate. Recently, it has been identified as a major contributor to hyperoxaluria, a disorder in which large deposits of calcium oxalate form kidney stones. Recombinant human HAO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Hydroxyacid oxidase 1, GOX (glycolate oxidase), GOX1, HAOX1. NCBI no.: NP_060015
    Molecular Weight
    45.0 kDa(406aa), confirmed by MALDI-TOF
    Pathways
    Monocarboxylic Acid Catabolic Process
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