HDDC3 Protein (AA 1-140) (His tag)
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- Target See all HDDC3 Proteins
- HDDC3 (HD Domain Containing 3 (HDDC3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-140
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HDDC3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HDDC3, 1-140aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HDDC3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
- Storage
- 4 °C
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- Target
- HDDC3 (HD Domain Containing 3 (HDDC3))
- Alternative Name
- HDDC3 (HDDC3 Products)
- Synonyms
- MESH1 Protein, zgc:110184 Protein, 1110033O09Rik Protein, C86475 Protein, RGD1311839 Protein, HD domain containing 3 Protein, HD domain containing 3 S homeolog Protein, hddc3 Protein, HDDC3 Protein, hddc3.S Protein, Hddc3 Protein
- Background
- HDDC3, also known as guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Recombinant human HDDC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, MESH1, ppGpp. NCBI no.: NP_940929
- Molecular Weight
- 17.9 kDa (160aa), confirmed by MALDI-TOF
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