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IDH1 Protein (AA 1-414) (His tag)

IDH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667603
  • Target See all IDH1 Proteins
    IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-414
    Origin
    • 10
    • 4
    • 3
    • 1
    • 1
    Human
    Source
    • 11
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IDH1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    IDH1, 1-414aa , Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product IDH1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT,0.1mM PMSF
    Storage
    4 °C
  • Target
    IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
    Alternative Name
    IDH1 (IDH1 Products)
    Synonyms
    IDCD Protein, IDH Protein, IDP Protein, IDPC Protein, PICD Protein, NADP-CICDH Protein, AI314845 Protein, AI788952 Protein, E030024J03Rik Protein, Id-1 Protein, Idh-1 Protein, Idpc Protein, cb876 Protein, fm90e09 Protein, im:7143416 Protein, wu:fm90e09 Protein, F23E12.180 Protein, F23E12_180 Protein, IDH-I Protein, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1 Protein, isocitrate dehydrogenase 1 Protein, isocitrate dehydrogenase I Protein, isocitrate dehydrogenase (NADP(+)) 1, cytosolic Protein, isocitrate dehydrogenase 1 (NADP+), soluble Protein, isocitrate dehydrogenase 1 (NADP+) L homeolog Protein, isocitrate dehydrogenase 1 Protein, IDH1 Protein, Idh1 Protein, idh1.L Protein, idh1 Protein
    Background
    IDH1, also known as isocitrate dehydrogenase (IDHC) cytoplasmic enzyme, belongs to the isocitrate and isopropylmalate dehydrogenases family. This protein catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming alpha-ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of alpha-ketoglutarate. Recombinant human IDH1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Isocitrate dehydrogenase [NADP] cytoplasmic, IDCD, IDH, IDP, IDPC, PICD. NCBI no.: NP_005887
    Molecular Weight
    48.8 kDa (434aa), confirmed by MALDI-TOF
    Pathways
    Warburg Effect
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