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AKR7A2 Protein (AA 1-359) (His tag)

AKR7A2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667763
  • Target See all AKR7A2 Proteins
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-359
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This AKR7A2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    AKR7A2, 1-359aa, Human, His tag, E. coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product AKR7A2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 20% glycerol
    Storage
    4 °C
  • Target
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Alternative Name
    AKR7A2 (AKR7A2 Products)
    Synonyms
    AFAR Protein, AFAR1 Protein, AFB1-AR1 Protein, AKR7 Protein, Aiar Protein, akr7a2 Protein, aldo-keto reductase family 7 member A2 Protein, aldo-keto reductase family 7, member A2 Protein, aldo-keto reductase family 7, member A2 L homeolog Protein, AKR7A2 Protein, Akr7a2 Protein, akr7a2.L Protein
    Background
    Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones. This protein can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the nonbinding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Also, it has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to gamma-Hydroxybutyrate in human brain. Recombinant AKR7A2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Aflatoxin B1 aldehyde reductase member 2, AFAR, AFAR1, AFB1-AR1, AKR7, aldo-keto reductase family 7, member A2 AFB1 AR1, AFB1AR1, aflatoxin aldehyde reductase, aflatoxin beta1 aldehyde reductase, Aiar, aldo keto reductase family 7, aldo keto reductase family 7, member A2, aldoketoreductase 7. NCBI no.: NP_003680
    Molecular Weight
    44.0kDa (398aa), confirmed by MALDI-TOF.
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