RAD1 Protein (AA 1-282) (His tag)
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- Target See all RAD1 Proteins
- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-282
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAD1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RAD1, 1-282aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RAD1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
- Alternative Name
- RAD1 (RAD1 Products)
- Synonyms
- HRAD1 Protein, REC1 Protein, zgc:56502 Protein, zgc:77779 Protein, RAD1 Protein, xrad1 Protein, DKFZp459H1127 Protein, RAD1 checkpoint DNA exonuclease Protein, RAD1 homolog (S. pombe) Protein, RAD1 Protein, Rad1 Protein, rad1 Protein
- Background
- RAD1 is a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. This complex also contains the Rad9 and Hus1 proteins and is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Recombinant human RAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HRAD1, REC1, Cell cycle checkpoint protein RAD1. NCBI no.: NP_002844
- Molecular Weight
- 33.9 kDa (302aa) confirmed by MALDI-TOF
- Pathways
- M Phase
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