SNRPF Protein (AA 1-86) (His tag)
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- Target See all SNRPF Proteins
- SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F (SNRPF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-86
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SNRPF protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SNRPF, 1-86aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SNRPF Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 1mM EDTA
- Storage
- 4 °C
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- Target
- SNRPF (Small Nuclear Ribonucleoprotein Polypeptide F (SNRPF))
- Alternative Name
- SNRPF (SNRPF Products)
- Synonyms
- BcDNA:GM23968 Protein, CG16792 Protein, Deb Protein, Deb-B Protein, DebB Protein, Dmel\\CG16792 Protein, dF Protein, deb-b Protein, snRNP-F Protein, sm-f Protein, smf Protein, snrpfl Protein, SMF Protein, Sm-F Protein, SmF Protein, 2010013O18Rik Protein, sm-F Protein, Small ribonucleoprotein particle protein SmF Protein, small nuclear ribonucleoprotein polypeptide F Protein, small nuclear ribonucleoprotein polypeptide F S homeolog Protein, SmF Protein, SNRPF Protein, snrpf Protein, Snrpf Protein, snrpf.S Protein
- Background
- Small nuclear ribonucleoprotein polypeptide F, also known SNRPF, belongs to the snRNP Sm proteins family. There are at least seven isoforms, E, F, G, D1, D2, D3 and B/B. This class of common proteins plays an essential role in the biogenesis of the snRNPs. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). SNRPF aid in the cytoplasmic construction of the UsnRNPs by binding to aconserved Sm site on UsnRNA and forming a stable snRNP core complex. Recombinant human SNRPF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Small nuclear ribonucleoprotein polypeptide F, Sm-F, SMF, PBSCF. NCBI no.: NP_003086
- Molecular Weight
- 11.8 kDa (106aa), confirmed by MALDI-TOF
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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