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LAMTOR2 Protein (AA 1-125) (His tag)

LAMTOR2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667853
  • Target See all LAMTOR2 Proteins
    LAMTOR2 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-125
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This LAMTOR2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    ROBLD3, 1-125aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product LAMTOR2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 2mM DTT, 10% glycerol
    Storage
    4 °C
  • Target
    LAMTOR2 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))
    Alternative Name
    ROBLD3 (LAMTOR2 Products)
    Synonyms
    ENDAP Protein, HSPC003 Protein, MAPBPIP Protein, MAPKSP1AP Protein, ROBLD3 Protein, Ragulator2 Protein, p14 Protein, 2010111E04Rik Protein, AL022628 Protein, Mapbpip Protein, P14 Protein, Rab25 Protein, Robld3 Protein, RGD1562501 Protein, cg5189 Protein, endap Protein, hspc003 Protein, mapbpip Protein, mapbpip-B Protein, mapksp1ap Protein, ragulator2 Protein, robld3 Protein, robld3-b Protein, zgc:100811 Protein, lamtor2 Protein, lamtor2-a Protein, lamtor2-b Protein, mapbpip-A Protein, robld3-a Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 S homeolog Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 L homeolog Protein, LAMTOR2 Protein, Lamtor2 Protein, lamtor2.S Protein, lamtor2 Protein, lamtor2.L Protein
    Background
    ROBLD3, also known as MAPBPIP, belongs to the GAMAD family. It is an adapter protein that enhances the efficiency of the MAP kinase cascade and facilitates the activation of MAPK2. ROBLD3 compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes. Recombinant human ROBLD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitogen-activated protein-binding protein-interacting protein, ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, p14. NCBI no.: NP_054736
    Molecular Weight
    16.0 kDa (149aa), confirmed by MALDI-TOF
    Pathways
    PI3K-Akt Signaling
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