SPSB1 Protein (AA 24-233) (His tag)
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- Target See all SPSB1 Proteins
- SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-233
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SPSB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SPSB1, 24-233aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SPSB1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay )
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))
- Alternative Name
- SPSB1 (SPSB1 Products)
- Synonyms
- SSB-1 Protein, SSB1 Protein, 1110014L01Rik Protein, 4930422J18Rik Protein, AI596360 Protein, AI854583 Protein, splA/ryanodine receptor domain and SOCS box containing 1 Protein, SPSB1 Protein, Spsb1 Protein
- Background
- SPRY domain-containing SOCS box protein 1 (SPSB1), also known as SSB1, is a member of the SOCS box protein subfamily. This protein contains a central SPRY domain and a C-terminal SOCS box. Although some of the SOCS protein subfamilies function as adaptors for a large family of ubiquitin-protein isopeptide ligases to regulate certain signaling pathways, the function of the SSB subfamily remains to be determined. SPSB1 may play an important role in enhancing the HGF-induced Erk-Elk-1-SRE pathway. Over expression of SPSB1 exhibited no effect on the basal level or epidermal growth factor-induced SRE-luciferase activity. Recombinant human SPSB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SPRY domain-containing SOCS box protein 1, SSB-1, SSB1. NCBI no.: NP_079382
- Molecular Weight
- 26.1 kDa (231aa) confirmed by MALDI-TOF
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