Nth Endonuclease III-Like 1 (NTHL1) (AA 1-312) protein (His tag)

Catalog No. ABIN667953

Product Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Protein Type: Recombinant

Protein Characteristics: AA 1-312

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: His tag

Application: SDS-PAGE (SDS)

Characteristics: NTHL1, 1-312aa, Human, His tag, E.coli

Purity: > 80 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT

Storage: 4 °C

Target Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Alternative Name: NTHL1 (NTHL1 Products)

Synonyms: psmc3 Protein, psmc3-a Protein, nth-like DNA glycosylase 1 S homeolog Protein, nthl1.S Protein

Background: NTHL1, also known as nth endonuclease III-like protein 1, is one of the enzyme that has been shown to act on a large number of oxidatively damaged DNA sites. It has an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. It acts on a damaged strand, 5' from the damaged site and incises damaged DNA at cytosines, thymines and guanines. Recombinant human NTHL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Endonuclease III-like protein 1, NTH1, OCTS3. NCBI no.: NP_002519

Molecular Weight: 36.6 kDa (332aa), confirmed by MALDI-TOF