PSME2 Protein (AA 1-239) (His tag)
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- Target See all PSME2 Proteins
- PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-239
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSME2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PSME2, 1-239aa, Human, His tag E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PSME2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
- Storage
- 4 °C
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- Target
- PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
- Alternative Name
- PSME2 (PSME2 Products)
- Synonyms
- unp309 Protein, PA28B Protein, PA28beta Protein, REGbeta Protein, AA589371 Protein, AI788882 Protein, PA28b Protein, proteasome activator subunit 2 Protein, proteasome (prosome, macropain) activator subunit 2 (PA28 beta) Protein, psme2 Protein, PSME2 Protein, Psme2 Protein
- Background
- PSME2, also known as proteasome (prosome, macropain) activator subunit 2, is an IFN-gamma inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. Downregulation of PSME2 results in abnormal proteasome activation and has been implicated in the development of intimal hyperplasia (IH) in animal models. Recombinant human PSME2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Proteasome (prosome, macropain) activator subunit 2, PA28B, PA28beta, REGbeta. NCBI no.: AAH72025
- Molecular Weight
- 29.5 kDa (259aa), confirmed by MALDI-TOF
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
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