Aurora Kinase B Protein (AURKB) (AA 1-344) (His tag)

Catalog No. ABIN668044

Product Details

Target: Aurora Kinase B (AURKB)

Protein Type: Recombinant

Protein Characteristics: AA 1-344

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Aurora Kinase B protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: Aurora Kinase B, 1- 344 aa, Human, His-tagged, Recombinant, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.5mM DTT, 20% glycerol, 0.1mM EDTA, 0.1mM EGTA, 0.1M NaCl, 0.1mM PMSF

Storage: 4 °C

Target Details

Target: Aurora Kinase B (AURKB)

Alternative Name: Aurora Kinase B (AURKB Products)

Synonyms: AIK2 Protein, AIM-1 Protein, AIM1 Protein, ARK2 Protein, AurB Protein, IPL1 Protein, PPP1R48 Protein, STK12 Protein, STK5 Protein, aurkb-sv1 Protein, aurkb-sv2 Protein, AIRK2 Protein, AL022959 Protein, Aik2 Protein, Aim1 Protein, Ark2 Protein, STK-1 Protein, Stk12 Protein, Stk5 Protein, Aur B Protein, Aurora B Protein, Aurora-B Protein, CG6620 Protein, DmAIRK2 Protein, DmAurB Protein, DmAuroraB Protein, Dmel\\CG6620 Protein, IAL Protein, IAL1 Protein, Ial Protein, aurB Protein, aurora B Protein, ARK-2 Protein, XAIRK2 Protein, aik2 Protein, aim-1 Protein, aim1 Protein, airk2 Protein, ark2 Protein, ipl1 Protein, stk12 Protein, stk5 Protein, CHUNP6896 Protein, fa09g06 Protein, stka Protein, wu:fa09g06 Protein, aurkb Protein, AIRK2-B Protein, XAIRK2-B Protein, aurkb-a Protein, aurkb-b Protein, xAurora-B-B Protein, aurora kinase B Protein, aurora B Protein, aurora kinase B S homeolog Protein, AURKB Protein, Aurkb Protein, aurB Protein, aurkb Protein, aurkb.S Protein

Background: Aurora Kinase B is a member of a family of mitotic serine/threonine kinases. Aurora Kinase B associates with chromosomes during prophase prior to relocalizing to the spindle at anaphase. Aurora Kinase B regulates chromosome segregation through the control of microtubule-kinetochore attachment and cytokinesis. Expression of Aurora Kinase B during the G2/M phase transition is tightly coordinated with histone H3 phosphorylation, while overexpression in many kinds of cancers. Recombinant human Aurora Kinase B, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serine/threonine-protein kinase 12, Aurora-B, AIK2, AIM1, ARK2, AurB, aurkb-sv1, aurkb-sv2, IPL1, STK12, aurkb, AIM1, AURKB, Aurora 1, STK1, STK5, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora related kinase 2, Aurora/IPL1 related kinase 2, Serine/theronine kinase 12, Serine/threonine protein kinase 12,. NCBI no.: NP_004208

Molecular Weight: 41.4 kDa (364aa), confirmed by MALDI-TOF.

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades