GDF5 Protein
-
- Target See all GDF5 Proteins
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Sequence
- APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
- Characteristics
-
Purified recombinant Human GDF5 protein
Expression System: E.coli
Bioactivity: Induction of alkaline phosphatase activity in ATDC5 cells: EC50 = 40Nm. - Purity
- > 98 % pure
- Top Product
- Discover our top product GDF5 Protein
-
Growth Differentiation Factor 5 (GDF5) (AA 376-495) protein (His tag)
GDF5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Growth Differentiation Factor 5 (GDF5) (AA 382-501) protein (His-IF2DI Tag)GDF5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Growth Differentiation Factor 5 (GDF5) (AA 28-127) protein (GST tag)GDF5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 5 (GDF5) (AA 382-501) protein (His tag)Crystallography grade GDF5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Growth Differentiation Factor 5 (GDF5) (AA 376-495) protein (His tag)Crystallography grade GDF5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Assay Procedure
-
Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 1.15 as the extinction coefficient for a 0.1 % (1 mg/mL) solution.
2. Analysis by RP-HPLC, using a standard solution of GDF5 as a Reference Standard. - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
-
- Target
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Alternative Name
- GDF5 (GDF5 Products)
- Synonyms
- CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein
- Background
-
GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Alternative Names: BMP-14 protein, LAP4 protein, Growth Differentiation Factor 5 protein, GDF 5 protein, GDF-5 protein, Cartilage-derived morphogenetic protein-1 protein, GDF-5 protein, Radotermin protein, CDMP1 protein, GDF5 protein, GDF 5, BMP14 protein, Growth differentiation factor 5 protein, GDF-5 protein, CDMP-1 protein, SYNS2 protein, CDMP1 protein, GDF5, GDF-5 - Molecular Weight
- 26.8 kDa
-
