CXCL1 Protein
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- Target See all CXCL1 Proteins
- CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Sequence
- APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV P
- Characteristics
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using rat neutrophils is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
- Purity
- > 97 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- Level Less than 1EU/µg of rRtGRO/CXCL1 as determined by LAL method
- Top Product
- Discover our top product CXCL1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Storage
- 4 °C
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- Target
- CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
- Alternative Name
- GRO alpha/cxcl1 (CXCL1 Products)
- Synonyms
- FSP Protein, GRO1 Protein, GROa Protein, MGSA Protein, MGSA-a Protein, NAP-3 Protein, SCYB1 Protein, CINC-1 Protein, Gro1 Protein, CXCL1 Protein, Sdf1 Protein, Fsp Protein, KC Protein, Mgsa Protein, N51 Protein, Scyb1 Protein, gro Protein, GRO Protein, Gro Protein, C-X-C motif chemokine ligand 1 Protein, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Protein, C-X-C motif chemokine ligand 12 Protein, chemokine (C-X-C motif) ligand 1 Protein, CXCL1 Protein, Cxcl1 Protein, Cxcl12 Protein, GRO1 Protein
- Background
- All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Synonym: GRO alpha/CXCL1, Rat. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
- Molecular Weight
- 7.8 kDa, a single, non-glycosylated polypeptide chain containing 72 amino acids.
- Pathways
- Autophagy
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