Browse our Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteins (SLC9A3R1)

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Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteins (SLC9A3R1)
On www.antibodies-online.com are 9 Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Proteins from 4 different suppliers available. Additionally we are shipping Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Antibodies (110) and many more products for this protein. A total of 124 Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 products are currently listed.
Synonyms:
EBP-50, EBP50, NHE-RF, NHERF, NHERF-1, NHERF1, NPHLOP2
list all proteins Gene Name GeneID UniProt
SLC9A3R1 26941 P70441
SLC9A3R1 9368 O14745
SLC9A3R1 59114 Q9JJ19

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Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteins (SLC9A3R1) by Origin

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Top referenced Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteins

  1. Human SLC9A3R1 Protein expressed in HEK-293 Cells - ABIN2732190 : Wang, Qin, Zhu: Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease. in The Journal of international medical research 2015 (PubMed)

More Proteins for Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Interaction Partners

Mouse (Murine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. The NHERF1 (show SLC9A3R2 Proteins) is as putative molecular organizer of signal transduction in vomeronasal neurons.

  2. we show here that NHERF1 (show SLC9A3R2 Proteins) loss from the PM is oncogenic in vivo through its influence on Wnt (show WNT2 Proteins)-APC (show APC Proteins)-beta-catenin (show CTNNB1 Proteins) and Hippo-YAP (show YAP1 Proteins) pathways.

  3. NHERF1 (show SLC9A3R2 Proteins) mediates ANG II (show AGT Proteins)-induced activation of renal NHE3 (show SLC9A3 Proteins), which requires coordination between IRBIT (show AHCYL1 Proteins) and the NHERF1 (show SLC9A3R2 Proteins) PDZ1 domain in binding and transporting NHE3 (show SLC9A3 Proteins)

  4. These results indicate that PTH (show PTH Proteins)-mediated inhibition of renal phosphate transport involves phosphorylation of S77 of the NHERF-1 PDZ I domain and the dissociation of NHERF-1/Npt2a (show SLC34A1 Proteins) complexes.

  5. Results strongly support an important role for NHERF1 (show SLC9A3R2 Proteins) in the regulation of Planar Cell Polarity signaling and the development of functional motile cilia.

  6. the activation of PTEN and NHERF-1 may impede the evolution of macrophages beyond the M1 into M2 phenotype in tumor microenvironment.

  7. Data show that interaction of the inducible nitric oxide synthase (iNOS (show NOS2 Proteins)) C-terminus with the PDZ domains of EBP50 protein or Pdzk1 (show PDZK1 Proteins) protein CAP70 (show PDZK1 Proteins) resulted greater nitric oxide (NO) synthesis.

  8. The expression of EBP50 was not significantly different in the pseudopregnant uterus and decreased in the uteri subjected to activation of delayed implantation.

  9. NHERF1 (show SLC9A3R2 Proteins) is differentially distributed to rafts and non-raft brush border membrane fractions of NHE3 (show SLC9A3 Proteins).

  10. EBP50 expression is induced by inflammatory stimuli and potentiates NF-kappaB (show NFKB1 Proteins) activation and inflammation in primary macrophages and VSMC.

Cow (Bovine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. study found mainly nuclear localization of EBP50 in interphase cells, and its redistribution to cytoplasm during mitosis parallel with its phosphorylation; PP2A (show PPP2R2B Proteins) was identified as an interacting protein of EBP50 during pro-, prometa-, meta-, ana (show BTG3 Proteins)-, telophase, and early cytokinesis

Human Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. This interaction is promoted by EPAC1 (show RAPGEF3 Proteins) activation, triggering its translocation to the plasma membrane and binding to NHERF1. Our findings identify a new CFTR (show CFTR Proteins)-interacting protein and demonstrate that cAMP activates CFTR (show CFTR Proteins) through two different but complementary pathways - the well-known PKA-dependent channel gating pathway and a new mechanism regulating endocytosis that involves EPAC1 (show RAPGEF3 Proteins).

  2. we show here that NHERF1 loss from the PM is oncogenic in vivo through its influence on Wnt (show WNT2 Proteins)-APC (show APC Proteins)-beta-catenin (show CTNNB1 Proteins) and Hippo-YAP (show YAP1 Proteins) pathways.

  3. High EBP50 expression is associated with cervical cancer.

  4. Using neutron spin echo spectroscopy (NSE (show ENO2 Proteins)), the authors show salt-concentration-dependent excitation of nanoscale motion at the tip of the C-terminal tail in the phosphomimic S339D/S340D mutant.

  5. data highlight sequences in PTHR that contribute to NHERF1 interaction and can be altered to prevent phosphorylation-mediated inhibition

  6. NHERF1 acts with PMCA2 (show ATP2B2 Proteins) to regulate HER2 (show ERBB2 Proteins) signaling and membrane retention in breast cancers

  7. COOH-terminal sequences mediate enhanced NHERF1 interaction and facilitate the localization of CFTR (show CFTR Proteins).

  8. Na/H exchanger regulatory factor 1 (NHERF1) expression Is downregulated in cisplatin-resistant HeLa cells.

  9. Wild-type NHERF1 acts as a tumour suppressor, while NHERF1 A190D mutation abolishes the tumour-suppressive effect in cancer cells, due to A190D mutation-mediated nuclear NHERF1 translocation and induction of YAP (show YAP1 Proteins) phosphorylation.

  10. the distribution of NHERF1 in ovarian cancer and reveals a different regulation of NHERF1 and EZRIN (show EZR Proteins) expression in ovarian tumors which represents the complexity of the molecular changes of this disease

Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Protein Profile

Protein Summary

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Alternative names and synonyms associated with Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1)

  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (SLC9A3R1)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (Slc9a3r1)
  • EBP-50 protein
  • EBP50 protein
  • NHE-RF protein
  • NHERF protein
  • NHERF-1 protein
  • NHERF1 protein
  • NPHLOP2 protein

Protein level used designations for SLC9A3R1

EBP50 , Na(+)/H(+) exchange regulatory cofactor NHE-RF1 , ezrin-radixin-moesin-binding phosphoprotein 50 , regulatory cofactor of Na(+)/H(+) exchanger , sodium-hydrogen exchanger regulatory factor 1 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 , solute carrier family 9 isoform A3 regulatory factor 1 , Na(+)/H(+) exchange regulatory cofactor NHE-RF , ezrin-radixin-moesin binding phosphoprotein-50 , solute carrier family 9 isoform 3 regulatory factor 1 , Na+/H+ exchange regulatory co-factor , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 , NHERF-1 , solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 , ERM-binding phosphoprotein

GENE ID SPECIES
26941 Mus musculus
505242 Bos taurus
9368 Homo sapiens
422108 Gallus gallus
59114 Rattus norvegicus
100009196 Oryctolagus cuniculus
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