N-Boc-Phe-Leu-Phe-Leu-Phe Peptide

Catalog No. ABIN399629

Product Details

Target: N-Boc-Phe-Leu-Phe-Leu-Phe

Purification: Rabbit Anti-CDC2 (Phospho-Tyr15) Polyclonal Antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Purity: > 95 %

Application Details

Restrictions: For Research Use only

Handling

Storage: -20 °C

References

Li, Wu, Wang, Wu, Song, Xian, Yuan, Pei, Shang: "Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells." in: Journal of neuroinflammation, Vol. 11, pp. 72, (2014) (PubMed).

Soehnlein, Zernecke, Eriksson, Rothfuchs, Pham, Herwald, Bidzhekov, Rottenberg, Weber, Lindbom: "Neutrophil secretion products pave the way for inflammatory monocytes." in: Blood, Vol. 112, Issue 4, pp. 1461-71, (2008) (PubMed).

Target Details

Target: N-Boc-Phe-Leu-Phe-Leu-Phe

Target Type: Peptide

Background: As a well-known FPR antagonist, formyl peptide receptor antagonist Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research. In regard to neutrophils, it was found that treatment of mice with Boc-PLPLP results in 40% reduction in neutrophil counts recovered in bronchoalveolar lavage fluid, compared with infected mice receiving placebo.