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ATP6AP2 antibody (AA 205-234)
ATP6AP2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB41871
unconjugated
Product Details anti-ATP6AP2 Antibody
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Target
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ATP6AP2
(ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))
Binding Specificity
All epitopes for ATP6AP2 antibodies
AA 205-234
Reactivity
All reactivities for ATP6AP2 antibodies
Human
Host
All hosts for ATP6AP2 antibodies
Rabbit
Clonality
All clonalities for ATP6AP2 antibodies
Polyclonal
Conjugate
All conjugates for ATP6AP2 antibodies
This ATP6AP2 antibody is un-conjugated
Application
All applications for ATP6AP2 antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ATP6AP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human ATP6AP2.
Clone
RB41871
Isotype
Ig Fraction
Top Product
Discover our top product ATP6AP2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
References for anti-ATP6AP2 antibody (ABIN1881092)
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Takahashi, Yamamoto, Hirose, Hiraishi, Shoji, Shibasaki, Kato, Kaneko, Sasano, Satoh, Totsune : "Expression of (pro)renin receptor in human kidneys with end-stage kidney disease due to diabetic nephropathy. " in: Peptides , Vol. 31 , Issue 7 , pp. 1405-8 , (2010 ) (PubMed ).
Cruciat, Ohkawara, Acebron, Karaulanov, Reinhard, Ingelfinger, Boutros, Niehrs : "Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. " in: Science (New York, N.Y.) , Vol. 327 , Issue 5964 , pp. 459-63 , (2010 ) (PubMed ).
Nabi, Biswas, Nakagawa, Ichihara, Inagami, Suzuki : "Prorenin has high affinity multiple binding sites for (pro)renin receptor. " in: Biochimica et biophysica acta , Vol. 1794 , Issue 12 , pp. 1838-47 , (2009 ) (PubMed ).
Alcazar, Cousins, Striker, Marin-Castano : "(Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling. " in: Experimental eye research , Vol. 89 , Issue 5 , pp. 638-47 , (2009 ) (PubMed ).
Takemitsu, Ichihara, Kaneshiro, Sakoda, Kurauchi-Mito, Narita, Kinouchi, Yamashita, Itoh : "Association of (pro)renin receptor mRNA expression with angiotensin-converting enzyme mRNA expression in human artery. " in: American journal of nephrology , Vol. 30 , Issue 4 , pp. 361-70 , (2009 ) (PubMed ).
Target Details for ATP6AP2
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Target
ATP6AP2
(ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))
Alternative Name
ATP6AP2 (ATP6AP2 Products )
Synonyms
APT6M8-9 antibody, ATP6IP2 antibody, ATP6M8-9 antibody, ELDF10 antibody, M8-9 antibody, MRXE antibody, MSTP009 antibody, XMRE antibody, (P)RR antibody, 5730403E06Rik antibody, Atp6ip2 antibody, tj6 antibody, wss antibody, arcl antibody, j6b7 antibody, stv1 antibody, tj6m antibody, tj6s antibody, vph1 antibody, atp6a2 antibody, atp6n1d antibody, ATP6AP2 antibody, DKFZp459G0918 antibody, atp6ap2 antibody, wu:fj36c03 antibody, wu:fq15e04 antibody, zgc:73194 antibody, ATPase H+ transporting accessory protein 2 antibody, ATPase, H+ transporting, lysosomal accessory protein 2 antibody, ATPase H+ transporting V0 subunit d2 antibody, ATPase H+ transporting V0 subunit a2 antibody, ATPase, H+ transporting, lysosomal accessory protein 2 S homeolog antibody, ATP6AP2 antibody, Atp6ap2 antibody, ATP6V0D2 antibody, atp6v0a2 antibody, atp6ap2.S antibody, atp6ap2 antibody
Background
This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
Molecular Weight
39008
NCBI Accession
NP_005756
UniProt
O75787
Pathways
ACE Inhibitor Pathway , Peptide Hormone Metabolism , Regulation of Systemic Arterial Blood Pressure by Hormones
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