Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kaspera, Kirby, Sahele, Collier, Kharasch, Unadkat, Totah: "Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo." in: Biochemical pharmacology, Vol. 91, Issue 1, pp. 109-18, (2014) (PubMed).
Lee, Jones, Katayama, Kaspera, Jiang, Freiwald, Smith, Walker, Totah: "Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 5, pp. 943-51, (2012) (PubMed).
Pearson, Warren, Barrett, Khan: "Detection of EETs and HETE-generating cytochrome P-450 enzymes and the effects of their metabolites on myometrial and vascular function." in: American journal of physiology. Endocrinology and metabolism, Vol. 297, Issue 3, pp. E647-56, (2009) (PubMed).
Target
CYP2J2
(Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2))