5-Carboxylcytosine antibody
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- Target
- 5-Carboxylcytosine
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- Dot Blot (DB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purification
- None
- Immunogen
- This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to KLH and recognizes 5-carboxylcytosine.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -20 °C
- Storage Comment
- Antibodies in solution can be stored at -20 °C for 2 years.
- Expiry Date
- 6 months
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5-Carboxylcytosine levels are elevated in human breast cancers and gliomas." in: Clinical epigenetics, Vol. 7, pp. 88, (2015) (PubMed).
: "Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development." in: PLoS ONE, Vol. 8, Issue 12, pp. e82881, (2014) (PubMed).
: "Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA." in: Nature, Vol. 506, Issue 7488, pp. 391-5, (2014) (PubMed).
: "Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing." in: Nature communications, Vol. 4, pp. 1517, (2013) (PubMed).
: "Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development." in: Cell research, Vol. 21, Issue 12, pp. 1670-6, (2011) (PubMed).
: "
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5-Carboxylcytosine levels are elevated in human breast cancers and gliomas." in: Clinical epigenetics, Vol. 7, pp. 88, (2015) (PubMed).
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- Target
- 5-Carboxylcytosine
- Target Type
- Chemical
- Gene ID
- 57279
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