Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Dong, Wodziak, Lowe: "Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8016-27, (2015) (PubMed).
Riener, Thiesler, Hellerbrand, Amann, Cathomas, Fritzsche, Dahl, Bahra, Weichert, Terracciano, Kristiansen: "Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas." in: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 10, pp. 1722-30, (2014) (PubMed).
Gray, Murray, Nowicki, Remnant, Scherl, Muller, Vojtesek, Hupp: "Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein." in: Protein science : a publication of the Protein Society, Vol. 22, Issue 9, pp. 1266-78, (2013) (PubMed).
Wayner, Quek, Ahmad, Ho, Loprieno, Zhou, Ellis, True, Liu: "Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine." in: The Prostate, Vol. 72, Issue 9, pp. 1023-34, (2012) (PubMed).
Darb-Esfahani, Fritzsche, Kristiansen, Weichert, Sehouli, Braicu, Dietel, Denkert: "Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma." in: Virchows Archiv : an international journal of pathology, Vol. 461, Issue 2, pp. 109-16, (2012) (PubMed).
Lepreux, Bioulac-Sage, Chevet: "Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 31, Issue 3, pp. 322-8, (2011) (PubMed).
Ambolet-Camoit, Bui, Pierre, Chevallier, Marchand, Coumoul, Garlatti, Andreau, Barouki, Aggerbeck: "2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 2, pp. 501-12, (2010) (PubMed).
Maslon, Hrstka, Vojtesek, Hupp: "A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin." in: Journal of molecular biology, Vol. 404, Issue 3, pp. 418-38, (2010) (PubMed).
Zhao, Lee, Brown, Molloy, Marx, Pavlakis, Boyer, Stockler, Kaplan, Breit, Sutherland, Henshall, Horvath: "Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling." in: Cancer research, Vol. 69, Issue 19, pp. 7696-703, (2009) (PubMed).