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Thus, overexpression of Arp11 may suppress tumorigenicity in nude mice.
This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.
actin-related protein 3B
, ARP3 actin-related protein 3 homolog B (yeast)
, actin-like protein 3B
, actin-related protein 3-beta
, actin-related protein ARP4
, actin-related protein Arp11
, ARP3 actin-related protein 3 homolog B