Browse our anti-KCNMA1 (KCNMA1) Antibodies

Full name:
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 Antibodies (KCNMA1)
On www.antibodies-online.com are 67 Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) Antibodies from 16 different suppliers available. Additionally we are shipping KCNMA1 Proteins (5) and many more products for this protein. A total of 81 KCNMA1 products are currently listed.
Synonyms:
5730414M22Rik, bA205K10.1, BKCa, bktm, cSlo, DDBDRAFT_0190653, DDBDRAFT_0235401, DDB_0190653, DDB_0235401, KCa1.1, Kcnma, kcnma1, kcnma1-A, KCNMA1b, KCNMA1c, MaxiK, mSlo, mSlo1, sakca, si:ch211-39f22.2, Slo, SLO-ALPHA, slo1
list all antibodies Gene Name GeneID UniProt
KCNMA1 3778 Q12791
KCNMA1 16531 Q08460
KCNMA1 83731 Q62976

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anti-Human KCNMA1 Antibodies:

anti-Mouse (Murine) KCNMA1 Antibodies:

anti-Rat (Rattus) KCNMA1 Antibodies:

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Top referenced anti-KCNMA1 Antibodies

  1. Cow (Bovine) Polyclonal KCNMA1 Primary Antibody for WB - ABIN2780204 : Cambien, Rezzonico, Vitale, Rouzaire-Dubois, Dubois, Barthel, Karimdjee, Soilihi, Mograbi, Schmid-Alliana, Schmid-Antomarchi: Silencing of hSlo potassium channels in human osteosarcoma cells promotes tumorigenesis. in International journal of cancer. Journal international du cancer 2008 (PubMed)

  2. Human Polyclonal KCNMA1 Primary Antibody for IF (p), IHC (p) - ABIN672426 : Sudduth, Weekman, Price, Gooch, Woolums, Norris, Wilcock: Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID). in Neuroscience 2016 (PubMed)

  3. Cow (Bovine) Polyclonal KCNMA1 Primary Antibody for ELISA - ABIN451811 : Yuan, OConnell, Wilson, Pietrzykowski, Treistman: Acute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against KCNMA1 Interaction Partners

Rabbit Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. High cholesterol can reduce the protein expression of BK channel beta1 subunit in rabbit Oddi's sphincter (SO) cells which suggests high cholesterol can affect the function of BKca channel [BK channel beta1 subunit]

  2. Aldosterone does not contribute to the regulation of BK channel expression/activity in response to dietary K(+) loading.

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. These results identify KCa1.1 channels as crucial regulators of skeletal myogenesis.

  2. Results show that reduced miR-17 expression is correlated with increased expression of KCNMA1 in malignant pleural mesothelioma. Computational analysis identified KCNMA1 gene is a direct target of miR-17.

  3. Our report defines a novel autosomal recessive KCNMA1-related epileptic phenotype that encompasses cerebellar atrophy without paroxysmal dyskinesia, and highlights the sensitivity of the developing brain to both increased and decreased activity of the KCNMA1-encoded channels

  4. A directed proteomic approach discovered the novel interaction of BKCa with Tom22 (show TOMM22 Antibodies), a component of the mitochondrion outer membrane import system, and the adenine nucleotide translocator (show SLC25A4 Antibodies) (ANT).

  5. GSK3b (show GSK3b Antibodies) may up-regulate BK channels, an effect disrupted by lithium or additional expression of AKT (show AKT1 Antibodies) and possibly participating in the regulation of cell volume and excitability.

  6. MiR (show MLXIP Antibodies)-31 represses KCNMA1 expression.

  7. By introducing lanthanide binding tags in the extracellular region of the alpha- or beta1-subunit, we determined (i) a basic extracellular map of the BK channel, (ii) beta1-subunit-induced rearrangements of the voltage sensor in alpha-subunits, and (iii) the relative position of the beta1-subunit within the alpha/beta1-subunit complex.

  8. Results indicate that silencing BKCa (KCa1.1) inhibits cell mobility, while silencing IKir (Kir2.1 (show KCNJ2 Antibodies)) increases cell mobility in human cardiac c-kit (show KIT Antibodies)+ progenitor cells.

  9. Suggest that BK channel modulation by auxiliary gamma subunits depends on intra- and/or juxta-membrane mechanisms.

  10. Suberoylanilide hydroxamic acid enhanced the expression of malignant genes such as KCNMA1 in lung cancer cells remaining after treatment, creating a more drug-resistant state.

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. Dynamic coupling between TRPV4 (show TRPV4 Antibodies) and Ca(2 (show CA2 Antibodies)+)-activated SK1 (show SPHK1 Antibodies)/3 and IK1 (show KCNN4 Antibodies) K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 in kidney collecting duct cells.

  2. The differential regulation of ROMK (show KCNJ1 Antibodies), large-conductance Ca(2 (show CA2 Antibodies)+)-activated K(+) (BK) channel, BK-alpha and NKCC2 (show SLC12A1 Antibodies) between female and male mice, at least, were partly mediated via WNK1 (show WNK1 Antibodies) pathway, which may contribute to the sexual dimorphism of plasma K(+) and blood pressure control.

  3. KCNMA1 contributes to the regulation of insulin (show INS Antibodies) signalling in mature adipocytes

  4. Results showed that BK-knockout osteoblasts displayed low proliferation and impaired mineralization ability providing further evidence that BK channel is critical for osteoblast function.

  5. GSK3b (show GSK3b Antibodies) may up-regulate BK channels, an effect disrupted by lithium or additional expression of AKT (show AKT1 Antibodies) and possibly participating in the regulation of cell volume and excitability.

  6. Data, including data from studies in knockout mice, suggest that association/disassociation of subunits Kcnma1 and Kcnab1 (show KCNAB1 Antibodies) of the BK channel (large-conductance calcium-activated potassium channel (show KCNAB2 Antibodies)) is involved in function of coronary artery smooth muscle cells and their dysfunction during ischemia/reperfusion-induced myocardial injury in diabetes.

  7. This study demonstrated that The interaction of MaxiK channel with GAT3 (show SLC6A13 Antibodies) opens the possibility of a role of MaxiK channel in GABA homeostasis and signaling.

  8. the enhanced effect of amiloride on potassium secretion in wild-type compared to knockout mice on the alkaline diet clarify a BK- alpha/beta4-mediated potassium secretory pathway in intercalated cells driven by ENaC (show SCNN1A Antibodies)-mediated sodium reabsorption

  9. Data suggest that the ion channels CaV1.3 (show CACNA1D Antibodies), bestrophin-1 (show BEST1 Antibodies) and maxiK were identified as players in the regulation of photoreceptor outer segments (POS) phagocytosis by the retinal pigment epithelium (RPE (show RPE Antibodies)).

  10. Data show that angiotensin II (Ang II) inhibited the current amplitude of Ca(2 (show CA2 Antibodies)+)-activated K(+) channels (BKCa) channel and decreased the slope of I-V curve.

Cow (Bovine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. analysis of SLO3 (show KCNU1 Antibodies) K+ channels shows evolutionary divergence for an RCK1 region of critical function

Xenopus laevis Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. A neural-specific splice-variant exon of Slo serves as a gain-of-function module and allows physiologically relevant levels of membrane potential and intracellular calcium to activate the resultant channel effectively during Xenopus embryogenesis.

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. Porcine K2P3.1 (show KCNK3 Antibodies) channels exhibit atrial expression and functional properties similar to their human orthologs, supporting a general role as antiarrhythmic drug targets.

  2. Inositol trisphosphate is an activator of BKCA channels in porcine coronary smooth muscle cells and exerts a coronary artery-relaxing effect.

  3. Testerone-induced relaxation of endothelium-denuded coronary arteries is mediated, at least in part, by enhanced NO production, leading to cGMP synthesis and PKG (show PRKG1 Antibodies) activation, which, in turn, opens BK(Ca) channels.

KCNMA1 Antigen Profile

Antigen Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with KCNMA1

  • calcium-activated BK potassium channel, alpha subunit (kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (KCNMA1) antibody
  • maxi-K channel alpha subunit (RBSLO1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (Kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1a (kcnma1a) antibody
  • 5730414M22Rik antibody
  • bA205K10.1 antibody
  • BKCa antibody
  • bktm antibody
  • cSlo antibody
  • DDBDRAFT_0190653 antibody
  • DDBDRAFT_0235401 antibody
  • DDB_0190653 antibody
  • DDB_0235401 antibody
  • KCa1.1 antibody
  • Kcnma antibody
  • kcnma1 antibody
  • kcnma1-A antibody
  • KCNMA1b antibody
  • KCNMA1c antibody
  • MaxiK antibody
  • mSlo antibody
  • mSlo1 antibody
  • sakca antibody
  • si:ch211-39f22.2 antibody
  • Slo antibody
  • SLO-ALPHA antibody
  • slo1 antibody

Protein level used designations for KCNMA1

calcium-activated potassium channel subunit alpha 1 , potassium large conductance calcium-activated channel, subfamily M, alpha member 1 , pulmonary calcium activated potassium channel , calcium-activated potassium channel subunit alpha-1-like , BK channel , BKCA alpha , KCa1.1 , calcium-activated potassium channel subunit alpha-1 , calcium-activated potassium channel, subfamily M subunit alpha-1 , k(VCA)alpha , large conductance calcium-activated potassium channel alpha subunit , maxi K channel , maxiK , rbSlo , slo homolog , slo-alpha , slo1 , slowpoke homolog , BK channel alpha subunit , BKCA alpha subunit , hSlo , maxi-K channel HSLO , stretch-activated Kca channel , calcium-activated potassium channel alpha subunit , bSlo , xSlo , MaxiK calcium-activated potassium channel , calcium activated potassium channel protein , large conductance calcium-activated potassium channel subfamily M alpha member 1 , large conductance calcium-activated potassium (BK) channel alpha subunit a , slo1a

GENE ID SPECIES
8617340 Dictyostelium discoideum AX4
100008593 Danio rerio
100270685 Ovis aries
100454095 Pongo abelii
100008745 Oryctolagus cuniculus
3778 Homo sapiens
16531 Mus musculus
83731 Rattus norvegicus
282573 Bos taurus
373712 Xenopus laevis
374065 Gallus gallus
403984 Canis lupus familiaris
397434 Sus scrofa
574103 Macaca mulatta
568554 Danio rerio
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