Browse our Major Histocompatibility Complex Class I C Proteins (HLAC)

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Major Histocompatibility Complex Class I C Proteins (HLAC)
On www.antibodies-online.com are 36 Major Histocompatibility Complex Class I C (HLAC) Proteins from 4 different suppliers available. Additionally we are shipping Major Histocompatibility Complex Class I C Antibodies (66) and Major Histocompatibility Complex Class I C Kits (3) and many more products for this protein. A total of 109 Major Histocompatibility Complex Class I C products are currently listed.
Synonyms:
D6S204, HLA-JY3, HLC-C, PSORS1
list all proteins Gene Name GeneID UniProt
HLAC 3107 P10321

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Human Major Histocompatibility Complex Class I C (HLAC) interaction partners

  1. The HLA-B*42, HLA-C*17, HLA-DPA1*03, and HLA-DPB1*105 genotypes were associated with allergic asthma and the HLA-B*48 genotype with the nonallergic phenotype.

  2. Genotyping analysis revealed that HLA-C2, which provides a ligand for killer-cell immunoglobulin-like receptors (KIR) expressed by NK cells, was strongly associated with psoriasis susceptibility. However, no link between the KIR genes themselves and disease was found

  3. the signal overall signal that NK cells receive from paternal HLA-C on trophoblasts depends on the ratio of activating and inhibitory KIR genes expressed by them

  4. Here we define the nature and extent of the variation in 3,489 HLA-A, 4,356 HLA-B and 3,111 HLA-C alleles. The common alleles of human populations comprise 42 core alleles, which represent all selected polymorphism, and recombinants that have assorted this polymorphism

  5. Data suggest that the immunoproteasome is involved in pathologic MHC class I (HLA-A, B, C, F and G) expression and maintenance of myokine production in Idiopathic inflammatory myopathies (IIMs).

  6. data strengthen our understanding of HLA-C transcriptional regulation and provide a basis for understanding the potential consequences of manipulating HLA-C levels therapeutically

  7. KIR2DS2 (show KIR2DS2 Proteins)/HLA-C1 may correlate with Hashimoto Thyroiditis pathogenesis.

  8. The data suggested the association of IL12B (show IL12B Proteins) with the psoriasis, however no evidence was observed for the epistatic effect of IL12B (show IL12B Proteins) with HLA-Cw6 among the psoriasis patients in India.

  9. this study first demonstrates hypermethylation of HLA-C gene in psoriatic epidermis, suggesting that HLA-C hypermethylation may be an epigenetic marker in psoriasis.

  10. This study suggests that HLA-A*66:01 might be a marker for cmarkers only in those of European ancestry cold medicine Stevens-Johnson Syndrome with ocular complications in Brazilian individuals of Pardo and European ancestry and that HLA-B*44:03 and HLA-C*12:03 might be .

Major Histocompatibility Complex Class I C (HLAC) Protein Profile

Protein Summary

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described

Alternative names and synonyms associated with Major Histocompatibility Complex Class I C (HLAC)

  • major histocompatibility complex, class I, C (HLA-C)
  • D6S204 protein
  • HLA-JY3 protein
  • HLC-C protein
  • PSORS1 protein

Protein level used designations for HLAC

HLA class I histocompatibility antigen, C alpha chain , HLA class I histocompatibility antigen, Cw-1 alpha chain , MHC class I antigen heavy chain HLA-C , human leukocyte antigen-C alpha chain , major histocompatibility antigen HLA-C

GENE ID SPECIES
3107 Homo sapiens
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