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Browse our anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies

Full name:
anti-Hepatitis A Virus Cellular Receptor 2 Antibodies (HAVCR2)
On www.antibodies-online.com are 199 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies from 23 different suppliers available. Additionally we are shipping Hepatitis A Virus Cellular Receptor 2 Proteins (35) and Hepatitis A Virus Cellular Receptor 2 Kits (7) and many more products for this protein. A total of 255 Hepatitis A Virus Cellular Receptor 2 products are currently listed.
Synonyms:
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
list all antibodies Gene Name GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

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Most Popular Reactivities for anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies

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Top referenced anti-Hepatitis A Virus Cellular Receptor 2 Antibodies

  1. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Show all 15 references for ABIN4896442

  2. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
    Show all 5 references for ABIN4896438

  3. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 references for ABIN4899648

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 3 references for ABIN4896162

  5. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896159 : Yadav, Jhunjhunwala, Phung, Lupardus, Tanguay, Bumbaca, Franci, Cheung, Fritsche, Weinschenk, Modrusan, Mellman, Lill, Delamarre: Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. in Nature 2014 (PubMed)
    Show all 2 references for ABIN4896159

  6. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Show all 2 references for ABIN4896440

  7. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 references for ABIN4896439

  8. Human Polyclonal HAVCR2 Primary Antibody for ELISA, WB - ABIN185571 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  9. Human Polyclonal HAVCR2 Primary Antibody for WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

  10. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

More Antibodies against Hepatitis A Virus Cellular Receptor 2 Interaction Partners

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The Tim-3/Gal-9 (show LGALS9 Antibodies) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. these data suggest that the high Tim-3 expression in monocytes could be utilized by tumor-promoting Gal-9 (show LGALS9 Antibodies) expression on CD4 (show CD4 Antibodies)(+) T cells

  2. In conclusion, Tim-3 on immune cells negatively regulates cell-mediated immunity against Plasmodium infection, and blocking Tim-3 signaling enhances sterile immunity and may play a protective role during malarial parasite infections.

  3. this study shows that the transcription factor T-bet controls Tim-3-mediated inhibition of monocyte/macrophage function during chronic hepatitis C virus infection

  4. this study shows that TIM-3 expressed on myeloid leukaemia cells may facilitate functional exhaustion in T helper cells

  5. this study shows that in osteosarcoma patients, Tim3 expression did not directly mediate immune suppression, but the interaction between Tim3+ T cells and monocytes, naive CD4 (show CD4 Antibodies)+ T cells, and Gal9-expressing CD4 (show CD4 Antibodies)+ CD25 (show IL2RA Antibodies)+ Tregs could resulting in progressive suppression of Th1 (show TH1L Antibodies) responses

  6. the present study demonstrated that interference with Tim-3 expression using siRNA may attenuate ccRCC invasion by aggravating anoikis following cell detachment.

  7. Elevated frequencies of CD8 (show CD8A Antibodies) T cells expressing PD-1 (show PDCD1 Antibodies), CTLA-4 (show CTLA4 Antibodies) and Tim-3 were found within tumor from perineural squamous cell carcinoma patients.

  8. Tim-3 blockade in combination with TLR activation induces the expression of antiviral molecules without a significant increase in TNF-alpha (show TNF Antibodies) or SOCS1 (show SOCS1 Antibodies).

  9. this study shows that the expression of TIM-3 is correlated with advanced stage and could be independent risk factors for colorectal cancer

  10. Immune checkpoint proteins are co-inhibitory factors that can diminish the antigen-specific immune responses by attenuating the regulatory role of cytotoxic T-lymphocyte-associated protein 4 (show CTLA4 Antibodies), programmed cell death-1 (show PDCD1 Antibodies), lymphocyte-activation gene 3 (show LAG3 Antibodies), and T-cell immunoglobulin mucin-3.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  2. in mice, TIM-3 is not essential for development of HDM (show HDAC3 Antibodies)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (show HDAC3 Antibodies)-induced chronic allergic airway inflammation.

  3. Authors found that a CD8 (show CD8A Antibodies)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  4. TIM4 (show TIMD4 Antibodies) binds TIM3 on the surface of polarized Th1 (show HAND1 Antibodies) cells to induce Th1 (show HAND1 Antibodies) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  5. The Gal-9 (show LGALS9 Antibodies)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  6. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  7. Tim-3 acts at a receptor-proximal point to enhance Lyn (show LYN Antibodies) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (show FCER1A Antibodies) ligation.

  8. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  9. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

  10. TIM-3 is highly expressed in hypoxic brain regions of a mouse cerebral hypoxia-ischaemia (H/I) model. TIM-3 is distinctively upregulated in activated microglia and astrocytes in a HIF-1 (show HIF1A Antibodies)-dependent manner.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2) antibody
  • hepatitis A virus cellular receptor 2 (Havcr2) antibody
  • HAVcr-2 antibody
  • HAVCR2 antibody
  • KIM-3 antibody
  • MGC140131 antibody
  • TIM-3 antibody
  • tim3 antibody
  • TIMD-3 antibody
  • Timd3 antibody

Protein level used designations for HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPECIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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