Browse our anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies

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anti-Hepatitis A Virus Cellular Receptor 2 Antibodies (HAVCR2)
On www.antibodies-online.com are 200 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibodies from 23 different suppliers available. Additionally we are shipping Hepatitis A Virus Cellular Receptor 2 Proteins (37) and Hepatitis A Virus Cellular Receptor 2 Kits (7) and many more products for this protein. A total of 258 Hepatitis A Virus Cellular Receptor 2 products are currently listed.
Synonyms:
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
list all antibodies Gene Name GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

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Top referenced anti-Hepatitis A Virus Cellular Receptor 2 Antibodies

  1. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Show all 15 references for 4896442

  2. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 references for 4899648

  3. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
    Show all 5 references for 4896438

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 3 references for 4896162

  5. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896159 : Yadav, Jhunjhunwala, Phung, Lupardus, Tanguay, Bumbaca, Franci, Cheung, Fritsche, Weinschenk, Modrusan, Mellman, Lill, Delamarre: Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. in Nature 2014 (PubMed)
    Show all 2 references for 4896159

  6. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 references for 4896439

  7. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Show all 2 references for 4896440

  8. Human Monoclonal HAVCR2 Primary Antibody for FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

  9. Dog (Canine) Polyclonal HAVCR2 Primary Antibody for WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

  10. Human Polyclonal HAVCR2 Primary Antibody for ELISA, WB - ABIN185571 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

More Antibodies against Hepatitis A Virus Cellular Receptor 2 Interaction Partners

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. The Tim-3/Gal-9 (show LGALS9 Antibodies) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. Osteosarcoma patients with higher Tim-3 had relatively lower survival. Multivariate analyses for overall survival revealed that high serum soluble Tim-3 level was an independent prognostic factor for osteosarcoma

  2. urther analyses revealed that the levels of Tim-3 on CD4 (show CD4 Antibodies)+ T cells and CD8 (show CD8A Antibodies)+ T cells exhibited different expression patterns in terms of localization depending on pathological category of prostate cancer and metastasis. Immunohistochemical analysis revealed that positive staining of Tim-3 in prostate cancer but little or no staining of Tim-3 was observed in benign prostate hyperplasia epithelium.

  3. this review discusses the recent findings on Tim-3, the role it plays in regulating immune responses in different cell types and the rationale for targeting Tim-3 for effective cancer immunotherapy

  4. The -1516G > T, -574G > T and +4259T > G SNPs within TIM-3 gene might play an important role as a genetic risk factor in the pathogenesis of ET.

  5. this study shows that that Tim-3 expression defines a subpopulation of PD-1 (show PDCD1 Antibodies)+ exhausted NY-ESO-1 (show CTAG1B Antibodies)-specific CD8 (show CD8A Antibodies)+ T cell and PD-1 (show PDCD1 Antibodies)+Tim-3+ CD8 (show CD8A Antibodies)+ T cells represented the largest subset of NY-ESO-1 (show CTAG1B Antibodies)-specific CD8 (show CD8A Antibodies)+ T cells in gastric cancer patients

  6. Increased TIM3+CD8 (show CD8A Antibodies)+T cells with lower perforin (show PRF1 Antibodies) and granzyme B (show Gzmb Antibodies) expression and higher CD95 (show FAS Antibodies) expression in MDS (show PAFAH1B1 Antibodies) patients had been observed. These findings suggested that TIM3 might be related to CD8 (show CD8A Antibodies)+T cells defect.

  7. our results suggested that PD-1 (show PDCD1 Antibodies) and TIM-3 blockade might be necessary in developing effective immunotherapeutic strategies in malignant Schwannoma, in which TIM-3 may play a more important role.

  8. these data suggest that the high Tim-3 expression in monocytes could be utilized by tumor-promoting Gal-9 (show LGALS9 Antibodies) expression on CD4 (show CD4 Antibodies)(+) T cells

  9. In conclusion, Tim-3 on immune cells negatively regulates cell-mediated immunity against Plasmodium infection, and blocking Tim-3 signaling enhances sterile immunity and may play a protective role during malarial parasite infections.

  10. this study shows that the transcription factor T-bet controls Tim-3-mediated inhibition of monocyte/macrophage function during chronic hepatitis C virus infection

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) interaction partners

  1. demonstrated that both IL-10 (show IL10 Antibodies) and TGF-beta (show TGFB1 Antibodies) upregulated TIM-3 surface expression on dendritic cells via a common signaling pathway that involved sequential activation of c-Src (show SRC Antibodies) and Bruton's tyrosine kinase (show BTK Antibodies)

  2. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  3. in mice, TIM-3 is not essential for development of HDM (show HDAC3 Antibodies)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (show HDAC3 Antibodies)-induced chronic allergic airway inflammation.

  4. Authors found that a CD8 (show CD8A Antibodies)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  5. TIM4 (show TIMD4 Antibodies) binds TIM3 on the surface of polarized Th1 (show HAND1 Antibodies) cells to induce Th1 (show HAND1 Antibodies) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  6. The Gal-9 (show LGALS9 Antibodies)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  7. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  8. Tim-3 acts at a receptor-proximal point to enhance Lyn (show LYN Antibodies) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (show FCER1A Antibodies) ligation.

  9. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  10. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2) antibody
  • hepatitis A virus cellular receptor 2 (Havcr2) antibody
  • HAVcr-2 antibody
  • HAVCR2 antibody
  • KIM-3 antibody
  • MGC140131 antibody
  • TIM-3 antibody
  • tim3 antibody
  • TIMD-3 antibody
  • Timd3 antibody

Protein level used designations for HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPECIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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