Browse our anti-PR Domain Containing 1, with ZNF Domain (PRDM1) Antibodies

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anti-PR Domain Containing 1, with ZNF Domain Antibodies (PRDM1)
On www.antibodies-online.com are 181 PR Domain Containing 1, with ZNF Domain (PRDM1) Antibodies from 25 different suppliers available. Additionally we are shipping PR Domain Containing 1, with ZNF Domain Proteins (9) and PR Domain Containing 1, with ZNF Domain Kits (3) and many more products for this protein. A total of 208 PR Domain Containing 1, with ZNF Domain products are currently listed.
Synonyms:
Blimp-1, BLIMP1, CG5249, dBlimp-1, dBlimp1, Dmel\\CG5249, GB11750, MGC52536, nrd, PRDI-BF1, PRDM1, ubo, wu:fb99c12, xblimp1, zgc:91885, ZNFPR1A1
list all antibodies Gene Name GeneID UniProt
PRDM1 639 O75626
PRDM1 12142 Q60636
PRDM1 309871  

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Top referenced anti-PR Domain Containing 1, with ZNF Domain Antibodies

  1. Human Monoclonal PRDM1 Primary Antibody for ChIP, ELISA - ABIN153174 : John, Clements, Russell, Garrett-Sinha: Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1. in The Journal of biological chemistry 2008 (PubMed)
    Show all 43 references for 153174

  2. Human Monoclonal PRDM1 Primary Antibody for ELISA, ICC - ABIN314189 : Liu, Leboeuf, Shi, Li, Wang, Shen, Garcia, Shen, Chen, Janin, Chen, Zhao: Rituximab plus CHOP (R-CHOP) overcomes PRDM1-associated resistance to chemotherapy in patients with diffuse large B-cell lymphoma. in Blood 2007 (PubMed)
    Show all 11 references for 314189

  3. Human Polyclonal PRDM1 Primary Antibody for ELISA, IHC - ABIN4284750 : Chang, Angelin-Duclos, Calame: BLIMP-1: trigger for differentiation of myeloid lineage. in Nature immunology 2001 (PubMed)

  4. Human Polyclonal PRDM1 Primary Antibody for ELISA, IHC - ABIN4284751 : Wang, Belguise, ONeill, Sánchez-Morgan, Romagnoli, Eddy, Mineva, Yu, Min, Trinkaus-Randall, Chalbos, Sonenshein: RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1. in Molecular and cellular biology 2009 (PubMed)

  5. Human Monoclonal PRDM1 Primary Antibody for FACS - ABIN4897745 : Kurioka, Ussher, Cosgrove, Clough, Fergusson, Smith, Kang, Walker, Hansen, Willberg, Klenerman: MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets. in Mucosal immunology 2015 (PubMed)

  6. Human Monoclonal PRDM1 Primary Antibody for FACS - ABIN4897747 : Traitanon, Mathew, La Monica, Xu, Mas, Gallon: Differential Effects of Tacrolimus versus Sirolimus on the Proliferation, Activation and Differentiation of Human B Cells. in PLoS ONE 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PRDM1 Primary Antibody for WB - ABIN2780353 : González-García, Ocaña, Jiménez-Gómez, Campos-Caro, Brieva: Immunization-induced perturbation of human blood plasma cell pool: progressive maturation, IL-6 responsiveness, and high PRDI-BF1/BLIMP1 expression are critical distinctions between antigen-specific and nonspecific plasma cells. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  8. Cow (Bovine) Polyclonal PRDM1 Primary Antibody for IHC, WB - ABIN2792524 : Diehl, Schmidlin, Nagasawa, van Haren, Kwakkenbos, Yasuda, Beaumont, Scheeren, Spits: STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Antibodies against PR Domain Containing 1, with ZNF Domain Interaction Partners

Rabbit PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. BLIMP1 (PRDM1)expression begins throughout the hypoblast at stage 1 and emerges in single primordial germ cell (PGC (show PGC Antibodies)) precursors in the posterior epiblast at stage 2.

Fruit Fly (Drosophila melanogaster) PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. The timing of shade expression is determined by its transcriptional activator betaFtz-f1. The betaftz-f1 gene is activated after a decline in the expression of its transcriptional repressor Blimp-1.

  2. Blimp-1 gene is transcribed during prepupal development when the ecdysteroid titer is high, but the expressed mRNA degrades rapidly.

  3. Blimp-1 regulates terminal differentiation of the tracheal system in the Drosophila embryo.

  4. These results suggest that the transient transcriptional repressor dBlimp-1 is important for determining developmental timing in the ecdysone-induced pathway.

Zebrafish PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. Expression of the M- and N-cadherins, previously implicated in driving adaxial cell migration, is largely unaffected by loss of Prdm1a function, suggesting that differential cadherin expression is not sufficient for adaxial cell migration

  2. Prdm1a functions as both a transcriptional activator and repressor during neural crest development.

  3. identify sox6 cis (show CISH Antibodies)-regulatory sequences that drive fast-twitch-specific expression in a Prdm1a-dependent manner

  4. prdm1a expression is upregulated in the absence of Notch (show NOTCH1 Antibodies) function, and inhibiting Notch (show NOTCH1 Antibodies) signaling fails to rescue prdm1a mutants

  5. prdm1a Regulates sox10 (show SOX10 Antibodies) and islet1 (show ISL1 Antibodies) in the development of neural crest and Rohon-Beard sensory neurons.

  6. These results indicate an essential role for prdm1a in the development of the zebrafish craniofacial skeleton.

  7. Here we show that the gene u-boot (ubo), a mutation in which disrupts the induction of embryonic slow-twitch fibers, encodes the zebrafish homolog of Blimp-1

  8. The transcriptional regulator Blimp-1 plays a role in the inception of Neural Crest progenitor fate through BMP signalling.

  9. prdm1/blimp1 has roles in embryo patterning and organogenesis

  10. prdm1 functions to promote the cell fate specification of both neural crest cells and sensory neurons

Human PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. these results provide novel clinical and biological insight into the tumor-suppressive role of PRDM1/BLIMP-1 in ABC (show ABCB6 Antibodies)-DLBCL patients and suggest that loss of PRDM1/BLIMP-1 function contributes to the overall poor prognosis of ABC (show ABCB6 Antibodies)-DLBCL patients.

  2. PRDM1 was identified as a susceptibility gene for systemic sclerosis.

  3. Data indicate that BTG2 (show BTG2 Antibodies), MAP3K11 (show MAP3K11 Antibodies), RPS6KA1 (show RPS6KA1 Antibodies) and PRDM1 as putative targets of microRNA miR (show MLXIP Antibodies)-125b.

  4. we identified MIR155HG and TERC to be transcriptionally downregulated by PRDM1 in two PRDM1-null NK-cell lines when it is ectopically expressed. These findings suggest that ZFAS1 and other dysregulated long non-coding RNAs may be involved in natural killer/T-cell lymphoma pathobiology through regulation of cancer-related genes, and loss-of-PRDM1 expression in natural killer/T-cell lymphomas tumorigenesis

  5. identified the Prdm1 gene encoding the B lymphocyte-induced maturation protein 1 as a crucial negative regulator of human TH17 cell differentiation

  6. B cell receptor signaling component, SYK (show SYK Antibodies), caused PAX5 (show PAX5 Antibodies) tyrosine phosphorylation in vitro and in cells. Transcriptional repression on the BLIMP1 promoter by PAX5 (show PAX5 Antibodies) was attenuated by this phosphorylation.

  7. Depletion of PRDM1 in lung cancer cells promotes cellular invasion and anoikis resistance in vitro and lung metastasis in vivo.

  8. Data show there was a positive correlation between B cell lymphoma 6 (Bcl-6 (show BCL6 Antibodies)) and B lymphocyte-induced maturation protein 1 (Blimp-1) at the level of mRNA.

  9. The PRDM1 expression appeared to play an essential role in Warthin tumour pathogenesis.

  10. Blimp-1 regulates the transcription of CS1 (show CSH1 Antibodies) gene in NK and B cell lines from multiple myeloma and diffuse large B cell lymphoma patients.

Mouse (Murine) PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. Blimp1 is required to maintain a highly proliferative luminal subset necessary for mammary gland development and homeostasis.

  2. Attenuated leptin-receptor (LEPR (show LEPR Antibodies)) expression is essential for the development and maintenance of acute lymphoblastic leukemia (ALL), and that fasting inhibits ALL development by upregulation of LEPR (show LEPR Antibodies) and its downstream signaling through the protein PR/SET domain 1 (PRDM1).

  3. role of Blimp-1 as a critical regulator of CD4 (show CD4 Antibodies) dysfunction and links it to the CD8 (show CD8A Antibodies) T cell dysfunctionality observed in infected mice.

  4. Contextual ablation of BLIMP-1 and p53 (show TP53 Antibodies) led to development of IgM (show CD40LG Antibodies)-positive B-cell lymphoma with an aggressive phenotype, supported by c-Myc (show MYC Antibodies) up-regulation, and accumulation of somatic mutations, as demonstrated by whole exome sequencing.

  5. this study shows that IL-10 (show IL10 Antibodies) production during B-cell development is strongly correlated with the expression level of Prdm1

  6. The escape of a fraction of Primordial germ cells from the Prdm1 deletion was sufficient to recover fairly normal germ cell pools, both in male and female adults

  7. There is a common program of effector T cell differentiation that is regulated by IL-2 and IL-12 signaling and the combined activities of the transcriptional regulators Blimp-1 and T-bet.

  8. Reduction of HDAC3 (show HDAC3 Antibodies) or NCoR1 (show NCOR1 Antibodies) expression by RNA interference in B cells resulted in an increased Prdm1 mRNA expression.

  9. TCF1 (show HNF1A Antibodies) is required for the T follicular helper cell response to viral infection functioning through negative feedback loops with IL-2 (show IL2 Antibodies) and Blimp1.

  10. Blimp1 was dispensable for survival of plasma cells. Blimp-1-deficient plasma cells retained their transcriptional identity but lost the ability to secrete antibody. Blimp-1 regulated many components of the unfolded protein response.

PR Domain Containing 1, with ZNF Domain (PRDM1) Antigen Profile

Antigen Summary

This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Alternative names and synonyms associated with PR Domain Containing 1, with ZNF Domain (PRDM1)

  • PR domain containing 1, with ZNF domain (PRDM1) antibody
  • PR domain containing 1, with ZNF domain (LOC100338324) antibody
  • Blimp-1 protein (Blimp-1) antibody
  • CG5249 gene product from transcript CG5249-RB (Blimp-1) antibody
  • blimp-1 (CpipJ_CPIJ007425) antibody
  • PR domain containing 1a, with ZNF domain (prdm1a) antibody
  • PR domain containing 1, with ZNF domain (prdm1) antibody
  • B lymphocyte induced maturation protein 1 (prdm1) antibody
  • PR domain containing 1, with ZNF domain (Prdm1) antibody
  • Blimp-1 antibody
  • BLIMP1 antibody
  • CG5249 antibody
  • dBlimp-1 antibody
  • dBlimp1 antibody
  • Dmel\\CG5249 antibody
  • GB11750 antibody
  • MGC52536 antibody
  • nrd antibody
  • PRDI-BF1 antibody
  • PRDM1 antibody
  • ubo antibody
  • wu:fb99c12 antibody
  • xblimp1 antibody
  • zgc:91885 antibody
  • ZNFPR1A1 antibody

Protein level used designations for PRDM1

PR domain containing 1, with ZNF domain , Blimp-1 protein , Blimp-1-PA , Blimp-1-PB , Blimp-1-PC , Blimp-1-PD , Blimp-1-PE , CG5249-PA , CG5249-PB , CG5249-PC , CG5249-PD , CG5249-PE , dBlimp1 , blimp-1 , B lymphocyte-induced maturation protein 1 , PR domain zinc finger protein 1 , PR domain-containing 1 , U boot , narrowminded , u-boot , B lymphocyte induced maturation protein 1 , PR domain zinc finger protein 1-like , B-lymphocyte-induced maturation protein 1 , BLIMP-1 , PRDI-binding factor-1 , beta-interferon gene positive-regulatory domain I binding factor , B lymphocyte induced maturation protein , PR domain containing 1 with ZNF domain , PR domain-containing protein 1 , beta-interferon gene positive regulatory domain I-binding factor

GENE ID SPECIES
100154284 Sus scrofa
100338324 Oryctolagus cuniculus
408295 Apis mellifera
38638 Drosophila melanogaster
6039439 Culex quinquefasciatus
323473 Danio rerio
380265 Xenopus laevis
446070 Takifugu rubripes
462904 Pan troglodytes
493207 Xenopus (Silurana) tropicalis
696757 Macaca mulatta
100071967 Equus caballus
100401970 Callithrix jacchus
100442042 Pongo abelii
100474321 Ailuropoda melanoleuca
100548130 Meleagris gallopavo
100560171 Anolis carolinensis
100585120 Nomascus leucogenys
100619194 Monodelphis domestica
639 Homo sapiens
12142 Mus musculus
445340 Gallus gallus
481947 Canis lupus familiaris
538384 Bos taurus
309871 Rattus norvegicus
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