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Human Corin ELISA Kit for Sandwich ELISA - ABIN2683864
Fathy, Abdel Hamid, Zabut, Jamee, Ali, Abu Mustafa: Diagnostic utility of BNP, corin and furin as biomarkers for cardiovascular complications in type 2 diabetes mellitus patients. in Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2015
Residues Lys (show LYZ ELISA Kits)-71, Phe-72 and Gln-73 serve as a novel retention motif in the intracellular pathway to regulate corin cell surface expression and activation.
N-glycans at different sites may play distinct roles in regulating the cell membrane targeting, zymogen activation, and ectodomain shedding of corin
These results provide the first experimental evidence that corin expression plays a role in cardiomyopathy by modulating myocardial fibrosis, cardiac function, heart failure, and survival.
Data show that KO/TgV mice had significantly higher levels of proatrial natriuretic peptide in the heart compared with that in control KO/TgWT mice, indicating that the corin variant was defective in processing natriuretic peptides in vivo.
Lack of corin in mice impairs their adaptive renal response to high dietary salt, suggesting that corin deficiency may represent an important mechanism underlying salt-sensitive hypertension.
results indicate that corin and ANP (show NPPA ELISA Kits) are essential for physiological changes at the maternal-fetal interface, suggesting that defects in corin and ANP (show NPPA ELISA Kits) function may contribute to pre-eclampsia
Data indicate that Corin's involvement in ANP (show NPPA ELISA Kits) processing is a key element in the heart's response to increased hemodynamic load
Ectodomain shedding and autocleavage of the cardiac membrane protease corin.
corin might be involved in the salt retention seen in glomerular diseases.
Insufficient corin activation is expected to prevent natriuretic peptide processing and may contribute to body fluid retention and impaired cardiac function in patients with heart failure.
Corin and atrial natriuretic peptide (show NPPA ELISA Kits) A (show NPPA ELISA Kits) were most abundant in the proximal convoluted tubules and the medullary connecting ducts.
CORIN expression is significantly downregulated in human masticatory mucosa during wound healing
serum levels of corin are significantly decreased in acute myocardial infarction patients
Data show that both furin (show FURIN ELISA Kits) and brain type natriuretic peptide (BNP) were more sensitive than corin in predicting cardiovascular complications in type 2 diabetes mellitus (T2DM) patients.
Circulating corin concentrations are related to infarct size in patients after ST-segment elevation myocardial infarction
Hypertensive participants had an increased serum corin level compared to those without hypertension, suggesting that corin may play a role in the pathology of hypertension.
Serum soluble corin was significantly and positively associated with dyslipidemia
Plasma corin levels decreased significantly from preoperative concentrations after coronary artery bypass graft surgery.
corin may play an important role in the pathology of atrial fibrillation
Increased serum soluble corin in mid pregnancy was associated with an increased risk for HDP(hypertensive disorders of pregnancy) .--increased serum soluble corin in mid pregnancy could be an indicator for HDP
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
corin, serine peptidase
, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN)
, atrial natriuretic peptide-converting enzyme-like
, atrial natriuretic peptide-converting enzyme
, low density lipoprotein receptor-related protein 4
, low density lipoprotein-related protein 4
, pro-ANP-converting enzyme
, heart-specific serine proteinase ATC2
, transmembrane protease serine 10