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Browse our SERPINF2 Proteins (SERPINF2)

Full name:
Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 Proteins (SERPINF2)
On www.antibodies-online.com are 3 Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) Proteins from 1 different suppliers available. Additionally we are shipping SERPINF2 Kits (8) and SERPINF2 Antibodies (8) and many more products for this protein. A total of 19 SERPINF2 products are currently listed.
Synonyms:
A2AP, AAP, AI747498, ALPHA-2-PI, API, PLI, Serpimf2, serpin
list all proteins Gene Name GeneID UniProt
SERPINF2 18816 Q61247
SERPINF2 5345 P08697
SERPINF2    

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SERPINF2 Proteins (SERPINF2) by Origin

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More Proteins for SERPINF2 Interaction Partners

Mouse (Murine) Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) interaction partners

  1. alpha2AP has a profibrotic effect probably not by the action as a plasmin (show PLG Proteins) inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis

  2. Alpha 2 antiplasmin is involved in the recruitment of lymphocytes in the peripheral tissues.Alpha 2 antiplasmin contributes to the maintenance of immunological functions that are related to IgE.

  3. Plasmin (show PLG Proteins)/alpha(2)-AP system played an important role in hepatic repair via clearance from the injury area.

  4. PgtE mediated degradation of the antiprotease alpha(2)-antiplasmin leads to functional inactivation of the antiprotease in infected macrophages

  5. alpha2-antiplasmin induction inhibits E-cadherin (show CDH1 Proteins) processing mediated by the plasminogen (show PLG Proteins) activator/plasmin (show PLG Proteins) system, leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion

  6. The lack of alpha2AP attenuated TGF-beta(1 (show TGFB1 Proteins)) synthesis, thereby resulting in attenuated fibrosis

  7. 2.65A X-ray crystal structure of an N-terminal truncated murine alpha(2)-antiplasmin.

  8. Results show that alpha2-antiplasmin is a critical regulator for vascular remodeling by inhibiting p53 (show TP53 Proteins)/p21 pathway.

Human Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) interaction partners

  1. alpha2AP has a profibrotic effect probably not by the action as a plasmin (show PLG Proteins) inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis

  2. Possession of the alpha2AP 407Lys allele was negatively associated with AAA (show APP Proteins), and thus changes in alpha2AP may affect aneurysm growth and development.

  3. Two differentially expressed proteins, alpha-1-antitrypsin (SERPINA1) and alpha-2 antiplasmin (SERPINF2) are associated with purpura fulminans.

  4. Data suggest serum A2AP (SERPINF2) level can serve as biomarker for diabetic retinopathy; levels of A2AP (but not fibrinogen, plasminogen (show PLG Proteins), or plasminogen activator inhibitor 1 (show SERPINE1 Proteins)) are up-regulated in hyperglycemic type 1 diabetes with retinopathy.

  5. Study revealed that plasmin (show PLG Proteins) was present in tumor tissue, and that it was responsible for processing progalanin to galanin (show GAL Proteins)(1-20) in the extracellular environment.

  6. Data suggest that decreased amounts of alpha2-plasmin (show PLG Proteins) inhibitor in plasma vs serum ex vivo may reflect reduced factor XIII (show UGDH Proteins) (FXIII) in vivo; thus, plasma vs serum alpha2-plasmin (show PLG Proteins) inhibitor may be useful diagnostic marker for severe FXIII deficiency.

  7. When the C terminus of alpha(2)-antiplasmin was removed, the binding affinity for active site-blocked plasmin (show PLG Proteins) remained high, suggesting additional exosite interactions between the serpin core and plasmin (show PLG Proteins).

  8. Truncation of monocyte chemoattractant protein 1 (show CCL2 Proteins) by plasmin (show PLG Proteins) promotes blood-brain barrier disruption.

  9. ADAMTS13 (show ADAMTS13 Proteins) inactivation by plasmin (show PLG Proteins) as a potential cause of thrombotic thrombocytopenic purpura

  10. Results describe the functional characterization of the unique plasmin (show PLG Proteins)(ogen)-binding region of the human alpha(2)-plasmin inhibitor.

Rabbit Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) interaction partners

SERPINF2 Protein Profile

Protein Summary

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SERPINF2

  • serine (or cysteine) peptidase inhibitor, clade F, member 2 (Serpinf2)
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2)
  • A2AP protein
  • AAP protein
  • AI747498 protein
  • ALPHA-2-PI protein
  • API protein
  • PLI protein
  • Serpimf2 protein
  • serpin protein

Protein level used designations for SERPINF2

alpha 2 antiplasmin , alpha-2-AP , alpha-2-PI , alpha-2-antiplasmin , alpha-2-plasmin inhibitor , pigment epithelium derived factor , plasmin inhibitor alpha 2 , serine (or cysteine) proteinase inhibitor, clade F, member 2 , serpin F2 , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 , alpha-2-PI serine protease inhibitor

GENE ID SPECIES
18816 Mus musculus
5345 Homo sapiens
100009515 Oryctolagus cuniculus
282522 Bos taurus
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