You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) Antibodies

Full name:
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Antibodies (PRKRA)
On www.antibodies-online.com are 89 Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) Antibodies from 14 different suppliers available. Additionally we are shipping Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Proteins (11) and many more products for this protein. A total of 110 Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator products are currently listed.
Synonyms:
AV120107, dyt16, im:7151758, lear, pact, PRK, PRKRA, prkra-a, prkra-b, rax, rbpa, zgc:162619
list all antibodies Gene Name GeneID UniProt
PRKRA 23992 Q9WTX2
PRKRA 311130 Q4V8C7
PRKRA 8575 O75569

Show all species

Show all synonyms

Most Popular Reactivities for anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) Antibodies

Select your species and application

anti-Mouse (Murine) Antibodies:

anti-Rat (Rattus) Antibodies:

anti-Human Antibodies:

All available anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Antibodies

Go to our pre-filtered search.

Top referenced anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Antibodies

  1. Human Polyclonal PRKRA Primary Antibody for EIA, WB - ABIN360037 : Seibler, Djarmati, Langpap, Hagenah, Schmidt, Brüggemann, Siebner, Jabusch, Altenmüller, Münchau, Lohmann, Klein: A heterozygous frameshift mutation in PRKRA (DYT16) associated with generalised dystonia in a German patient. in The Lancet. Neurology 2008 (PubMed)
    Show all 3 references for ABIN360037

  2. Human Polyclonal PRKRA Primary Antibody for EIA - ABIN358519 : Kok, Ng, Ching, Jin: Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN358519

  3. Cow (Bovine) Polyclonal PRKRA Primary Antibody for IHC, WB - ABIN2778859 : Lee, Hur, Park, Kim, Suh, Kim: The role of PACT in the RNA silencing pathway. in The EMBO journal 2006 (PubMed)
    Show all 2 references for ABIN2778859

  4. Human Monoclonal PRKRA Primary Antibody for IHC (p), IP - ABIN563706 : Surova, Akbar, Zhivotovsky: Knock-down of core proteins regulating microRNA biogenesis has no effect on sensitivity of lung cancer cells to ionizing radiation. in PLoS ONE 2012 (PubMed)

More Antibodies against Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Interaction Partners

Mouse (Murine) Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) interaction partners

  1. Data (including data from studies in transgenic/knockout mice) suggest that PACT/RAX (protein activator of protein kinase (show CDK7 Antibodies) R) functions as negative regulator of PKR/Eif2ak2 (show EIF2AK2 Antibodies) (protein kinase (show CDK7 Antibodies) R) in development of postnatal anterior pituitary tissue.

  2. Deficiency of PKR (show EIF2AK2 Antibodies) diminished peripheral inflammatory responses following E. coli

  3. The protein kinase (show CDK7 Antibodies) PKR (show EIF2AK2 Antibodies) is critical for LPS (show TLR4 Antibodies)-induced iNOS (show NOS2 Antibodies) production but is dispensable for inflammasome activation in macrophages.

  4. These observations identified a specific mutation that reduces steady-state levels of RAX (show RAX Antibodies) protein and disrupts the dsRNA binding function of the protein, demonstrating the importance of the Prkra gene in various aspects of mouse development.

  5. RAX (show RAX Antibodies) phosphorylation at serine 18 is required for PKR (show EIF2AK2 Antibodies) activation and consequent translation inhibition

  6. Study demonstrated an essential role of PACT (show RBBP6 Antibodies) in mammalian ear development and produced the first animal model.

  7. The role of PACT (show RBBP6 Antibodies) in mediating gene induction, PKR (show EIF2AK2 Antibodies) activation, and apoptosis in response to diverse stimuli

  8. TRBP (show TARBP2 Antibodies) controls PACT (show RBBP6 Antibodies) activation of PKR (show EIF2AK2 Antibodies), an activity that is reversed by stress.

  9. The authors demonstrate for the first time that PACT (show RBBP6 Antibodies) is phosphorylated in response to tunicamycin and is responsible for PKR (show EIF2AK2 Antibodies) activation by direct interaction.

  10. Study revealed a physiologically significant role for PACT (show RBBP6 Antibodies) in cell proliferation and an essential role of a dsRNA-binding protein in mammalian pituitary expansion.

Human Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) interaction partners

  1. MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR (show PKLR Antibodies) Activator PACT (show RBBP6 Antibodies) in Human Hepatic Stellate Cells.

  2. The interferon (show IFNA Antibodies)-induced protein kinase (show CDK7 Antibodies)(PACT (show RBBP6 Antibodies)) partially rescued defects of interferon (show IFNA Antibodies)-beta1 and chemokine (C-C motif) ligand 5/RANTES (show CCL5 Antibodies) (regulated on activation normal T cell expressed and secreted) induction in DDX3 (show DDX3X Antibodies)-knockdown HEK293 cells.

  3. These findings support a model in which a measles virus defective interfering RNA is sensed by PACT (show RBBP6 Antibodies) and RIG-I (show DDX58 Antibodies) to initiate an innate antiviral response via activation of interferon-beta (show IFNB1 Antibodies) production.

  4. this study demonstrates for the first time that OV20.0 of Orf virus is also able to interact with the dsRNA binding domain of PACT (show RBBP6 Antibodies) and that the presence of dsRNA strengthened the interaction of these two molecules.

  5. the affinity of PACT-PACT (show RBBP6 Antibodies) and PACT (show RBBP6 Antibodies)-PKR (show PKLR Antibodies) interactions is enhanced in dystonia patient lymphoblasts, thereby leading to intensified PKR (show PKLR Antibodies) activation and enhanced cellular death.

  6. Altered PRKRA signalling and C / EBPbeta expression is associated with HLA-B27 expression in monocytic cells.

  7. This stuidy provides the first independent replication of the DYT16 locus at 2q31.2 and strongly confirms the causal contribution of the PRKRA gene to DYT16. Our data suggest worldwide involvement of PRKRA in dystonia.

  8. NS1 (show PTPN11 Antibodies) prevents PACT (show RBBP6 Antibodies) from interacting with an essential component of the virus.

  9. PKR (show PKLR Antibodies) is activated in uninfected cells, specifically during mitosis, by binding to dsRNAs formed by inverted Alu repeats (IRAlus).

  10. In contrast to its previously described activity, PACT (show RBBP6 Antibodies) contributes to PKR (show PKLR Antibodies) dephosphorylation during HIV-1 replication.

Cow (Bovine) Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) interaction partners

  1. Tumour necrosis factor alpha (show TNF Antibodies) up-regulates protein kinase (show CDK7 Antibodies) R (PKR (show EIF2AK2 Antibodies))-activating protein (PACT, PRKRA) and increases phosphorylation of PKR (show EIF2AK2 Antibodies) and eukaryotic initiation factor (show EIF4G1 Antibodies) 2-alpha in articular chondrocytes.

Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) Antigen Profile

Antigen Summary

This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA)

  • protein kinase, interferon-inducible double stranded RNA dependent activator (PRKRA) antibody
  • protein kinase, interferon-inducible double stranded RNA dependent activator (LOC100354780) antibody
  • protein kinase, interferon inducible double stranded RNA dependent activator (Prkra) antibody
  • protein kinase, interferon-inducible double stranded RNA dependent activator (prkra) antibody
  • AV120107 antibody
  • dyt16 antibody
  • im:7151758 antibody
  • lear antibody
  • pact antibody
  • PRK antibody
  • PRKRA antibody
  • prkra-a antibody
  • prkra-b antibody
  • rax antibody
  • rbpa antibody
  • zgc:162619 antibody

Protein level used designations for PRKRA

protein kinase, interferon-inducible double stranded RNA dependent activator , interferon-inducible double stranded RNA-dependent protein kinase activator A-like , PKR-associated protein X , PKR-associating protein X , interferon-inducible double stranded RNA-dependent protein kinase activator A , protein activator of the interferon-induced protein kinase , protein kinase, interferon-inducible double stranded RNA-dependent activator , interferon-inducible double stranded RNA-dependent protein kinase activator A homolog , double-stranded RNA-binding protein A , interferon-inducible double stranded RNA-dependent protein kinase activator A homolog A , interferon-inducible double stranded RNA-dependent protein kinase activator A homolog B , xlRBPA

GENE ID SPECIES
459776 Pan troglodytes
703063 Macaca mulatta
100155653 Sus scrofa
100354780 Oryctolagus cuniculus
100477392 Ailuropoda melanoleuca
100596448 Nomascus leucogenys
23992 Mus musculus
311130 Rattus norvegicus
8575 Homo sapiens
488423 Canis lupus familiaris
282875 Bos taurus
557370 Danio rerio
379187 Xenopus laevis
Selected quality suppliers for anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) Antibodies
Did you look for something else?