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anti-Immunoglobulin A (IgA) secondary antibodies

Immunoglobulin A (IgA) plays a role in mucosal immunity and is produced in mucosal linings. Hence IgA can be found in mucous secretions, including tears, saliva, colostrum, secretions from the gastrointestinal tract, and others, but it is found only in small amounts in blood.

There are two isotypes, IgA1 (90%) and IgA2 (10%), with IgA1 being found in serum and produced in bone marrow B cells, and IgA2, being secreted into colostrum, maternal milk, tears and saliva. IgA can exist as a monomer or in a dimeric form called secretory IgA (sIgA). The secretory IgA consists of polymers of two IgA monomers linked by additional so-called J-chains and a secretory component that is wrapped around the IgA dimer in order to protect it from proteolytic digestion in the intestinal tract.

The list below contains a selection of anti-IgA antibodies:


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