anti-Immunoglobulin E (IgE) secondary antibodies

IgE is only found in mammals. IgE is the least abundant isotype of all antibodies, but it is capable of triggering the most powerful immune reactions. IgE plays an important role in allergy, and leads to excessive activation of mast cells and basophils by binding to their Fc receptors, resulting in an extreme inflammatory response.

Except its established function for allergy, there is still speculation about the physiological contributions of IgE. In animal models circumstantial evidence hints to IgE fighting gut parasites like parasitic worms, but this has not been conclusively proven in humans. IgE may play some role in the immune system’s recognition of cancer. However, so far there is only circumstantial evidence for this hypothesis though, like for example the observation that the prevalence of several cancers is lower in individuals with allergies. Additionally, treatment with immunesystem-suppressing substances increases the cancer risk. Interestingly, individuals with allergies have lower level of toxins. It is thought possible, that IgE bind an help to destroy or excrete toxins.

Below you will find a list of anti-Immunglobulin E (IgE) secondary antibodies.

anti-Immunoglobulin E
Reactivity	Host	Unconj.	AP	Biotin	FITC	HRP	TRITC	Texas Red
Human	Goat	ABIN336559	ABIN336560	ABIN336561	ABIN336562	ABIN336563	ABIN336564	ABIN336565
Human (Fc)	Mouse	ABIN135648	ABIN135649	ABIN135651	-	ABIN135650	-	-
Human (Fc)	Mouse	ABIN135673	ABIN135674	ABIN135676	-	ABIN135675	-	-
Human (Fc)	Mouse	ABIN135034	ABIN135036	ABIN135038	-	ABIN135035	ABIN135037	-