Browse our anti-DPYD (DPYD) Antibodies

Full name:
anti-Dihydropyrimidine Dehydrogenase Antibodies (DPYD)
On www.antibodies-online.com are 54 Dihydropyrimidine Dehydrogenase (DPYD) Antibodies from 16 different suppliers available. Additionally we are shipping DPYD Kits (41) and DPYD Proteins (7) and many more products for this protein. A total of 104 DPYD products are currently listed.
Synonyms:
14.t00017, AI315208, DDBDRAFT_0189681, DDBDRAFT_0231100, DDB_0189681, DDB_0231100, DHP, DHPDHASE, DPD, dpyd, E330028L06Rik, zgc:77205

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anti-Mouse (Murine) DPYD Antibodies:

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More Antibodies against DPYD Interaction Partners

Human Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. Exploring an extended set of deleterious DPYD variants improves the performance of DPYD genotyping for predicting both grade 3-4 and grade 4 toxicities (digestive and/or neurologic and/or hematotoxicities) related to capecitabine, as compared to conventional genotyping restricted to consensual variants *2A, *13 and D949V

  2. Combined expression analyses of hENT1, TS, and DPD may predict long-term outcomes in patients with borderline resectable pancreatic cancer after neoadjuvant chemoradiotherapy

  3. We demonstrated that real-time DPYD genotyping using TaqMan probes is cost effective in all fluoropyrimidine-based treatments

  4. In pancreatic neuroendocrine neoplasms, biochemical response (p = 0.005) and high dihydropyrimidine-dehydrogenase expression (p = 0.018) were predictive markers of response to 5-FU-based chemotherapy. Thymidylate-Synthase (show TYMS Antibodies) deficiency was an independent risk factor for shorter progression-free survival.

  5. ERCC1 (show ERCC1 Antibodies)-SNP in combination with mRNA ERCC1 (show ERCC1 Antibodies), DPYD, and ERBB2 (show ERBB2 Antibodies) from pretherapeutic endoscopic biopsies can predict minor response to chemoradiation, as a basis for individualized therapy of advanced esophageal cancer.

  6. Fourteen out of 275 cancer patients (5.1%) carried a DPYD variant and received a 25-50% dose reduction recommendation for 5-fluorouracil or capecitabine. None of the patients with a DPYD variant treated with a reduced dose developed toxicities.

  7. findings showed that almost 57.1% of Chinese colorectal cancer patients had at least one variant of DPYD*5A and DPYD*9A

  8. High levels of intratumoral DPD expression have a negative impact on sensitivity to 5-fluorouracil in gastric cancer patients, but no prognostic value for long-term survival was uncovered. (Meta-analysis)

  9. Reprot strong functional effect of a DPYD haplotype upon a phenotypic marker of individual 5-FU metabolism to improve toxicity prediction.

  10. we believe that developing functional testing at the bedside could probably help to better picture the actual DPD status of patients scheduled for fluorouracil-based therapy, so as to propose subsequent appropriate adaptive dosing strategies.

Mouse (Murine) Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. DPD gene expression is regulated first at the mRNA level when the hepatocytes enter the cell cycle. There is little regulation at the translational level. Cell proliferation rate is influences the enzyme activity modification.

Pig (Porcine) Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. Data show that dihydropyrimidine dehydrogenase residue H673 is required for active site closure, while S670 is important for substrate recognition.

DPYD Antigen Profile

Antigen Summary

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with DPYD

  • dihydropyrimidine dehydrogenase (DPYD) antibody
  • dihydropyrimidine dehydrogenase b (dpydb) antibody
  • dihydropyrimidine dehydrogenase (dpyd) antibody
  • dihydropyrimidine dehydrogenase (EHI_012980) antibody
  • dihydropyrimidine dehydrogenase (AaeL_AAEL014199) antibody
  • dihydropyrimidine dehydrogenase (AaeL_AAEL010204) antibody
  • dihydropyrimidine dehydrogenase (EDI_044620) antibody
  • dihydropyrimidine dehydrogenase (pyd1) antibody
  • dihydropyrimidine dehydrogenase (Dpyd) antibody
  • dihydropyrimidine dehydrogenase (LOC100356889) antibody
  • 14.t00017 antibody
  • AI315208 antibody
  • DDBDRAFT_0189681 antibody
  • DDBDRAFT_0231100 antibody
  • DDB_0189681 antibody
  • DDB_0231100 antibody
  • DHP antibody
  • DHPDHASE antibody
  • DPD antibody
  • dpyd antibody
  • E330028L06Rik antibody
  • zgc:77205 antibody

Protein level used designations for DPYD

DHPDHase , DPD , dihydropyrimidine dehydrogenase [NADP(+)] , dihydrothymine dehydrogenase , dihydrouracil dehydrogenase , dihydropyrimidine dehydrogenase

GENE ID SPECIES
100173131 Pongo abelii
457047 Pan troglodytes
715672 Macaca mulatta
100057177 Equus caballus
405829 Danio rerio
447312 Xenopus laevis
3410647 Entamoeba histolytica HM-1:IMSS
5563876 Aedes aegypti
5573038 Aedes aegypti
5882869 Entamoeba dispar SAW760
8616259 Dictyostelium discoideum AX4
100604410 Nomascus leucogenys
81656 Rattus norvegicus
1806 Homo sapiens
99586 Mus musculus
100727906 Cavia porcellus
397109 Sus scrofa
281124 Bos taurus
479935 Canis lupus familiaris
429083 Gallus gallus
101109311 Ovis aries
100356889 Oryctolagus cuniculus
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