DPYD antibody (AA 1-110)

Catalog No. ABIN560640

Cited in 1 publication. The Mouse Monoclonal anti-DPYD antibody (Clone 7D4) (ABIN560640) specifically detects DPYD in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for DPYD antibody (AA 1-110) (ABIN560640)

Target: DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPYD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 7D4

Product Details anti-DPYD Antibody

Binding Specificity: AA 1-110

Purpose: Mouse monoclonal antibody raised against a partial recombinant DPYD.

Sequence: MAPVLSKDSA DIESILALNP RTQTHATLCS TSAKKLDKKH WKRNPDKNCF NCEKLENNFD DIKHTTLGER GALREAMRCL KCADAPCQKS CPTNLDIKSF ITSIANKNYY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DPYD (NP_000101, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DPYD antibody (ABIN560640)

Kuilenburg, Meijer, Tanck, Dobritzsch, Zoetekouw, Dekkers, Roelofsen, Meinsma, Wymenga, Kulik, Büchel, Hennekam, Largiadèr: "Phenotypic and clinical implications of variants in the dihydropyrimidine dehydrogenase gene." in: Biochimica et biophysica acta, Vol. 1862, Issue 4, pp. 754-62, (2016) (PubMed).

Target Details for DPYD

Target: DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

Alternative Name: DPYD

Background: Full Gene Name: dihydropyrimidine dehydrogenase
Synonyms: DHP,DHPDHASE,DPD,MGC132008,MGC70799

Gene ID: 1806

NCBI Accession: NM_000110

Pathways: Ribonucleoside Biosynthetic Process