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anti-Human DDR2 antibody for Enzyme Immunoassay

Recommended DDR2 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
  • AW495251
  • DDR2
  • ddr2
  • MIG20a
  • NTRKR3
  • Ntrkr3
  • si:ch211-193c2.1
  • TKT
  • Tyro10
  • tyro10
  • TYRO10
Epitope
AA 304-320, AA 297-327
19
14
13
6
4
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
64
29
4
1
Host
Rabbit
65
22
Clonality
Polyclonal
Conjugate
This DDR2 antibody is un-conjugated
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
75
53
33
12
10
6
3
2
1
1
Supplier
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Catalog No. ABIN359956
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008833851 ABIN359957 EIA WB Rabbit Ig Log in to see Polyclonal 5
0.0008833851 ABIN1105936 EIA IF IHC (p) WB Mouse IgG2a Log in to see 3B11E4 3

Top referenced anti-DDR2 antibody for Enzyme Immunoassay

Similar anti-DDR2 Antibodies

Application / Reactivity Human
ELISA 38 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 18 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Western Blotting (WB) 58 Antibodies

General

Antigen Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
Epitope AA 304-320, AA 297-327
(19), (14), (13), (6), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(64), (29), (4), (1)
Host Rabbit
(65), (22)
Clonality
Polyclonal
Conjugate This DDR2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(75), (53), (33), (12), (10), (6), (3), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-DDR2 Antibody

Target Details DDR2 Application Details Handling References for anti-DDR2 Antibody (ABIN359956) Images
Specificity This antibody recognizes DDR2 (TYRO10).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 297~327 amino acids from aa 304~320 of Human TYRO10.
Isotype Ig

Target Details DDR2

Product Details anti-DDR2 Antibody Application Details Handling References for anti-DDR2 Antibody (ABIN359956) Images back to top
Antigen
Alternative Name CD167b / DDR2 (DDR2 Antibody Abstract)
Background Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.Synonyms: CD167 antigen-like family member B, Discoidin domain-containing receptor 2, Discoidin domain-containing receptor tyrosine kinase 2, NTRKR3, Neurotrophic tyrosine kinase receptor-related 3, Receptor protein-tyrosine kinase TKT, TKT, TYRO10, Tyrosine-protein kinase TYRO10
Gene ID 4921, 9606
UniProt Q16832
Pathways RTK Signaling

Application Details

Product Details anti-DDR2 Antibody Target Details DDR2 Handling References for anti-DDR2 Antibody (ABIN359956) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details References for anti-DDR2 Antibody (ABIN359956) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-DDR2 Antibody (ABIN359956)

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling Images back to top
Background publications

Vogel, Gish, Alves, Pawson: "The discoidin domain receptor tyrosine kinases are activated by collagen." in: Molecular cell, Vol. 1, Issue 1, pp. 13-23, 1998

Edelhoff, Sweetser, Disteche: "Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C." in: Genomics, Vol. 25, Issue 1, pp. 309-11, 1995

Karn, Holtrich, Bräuninger, Böhme, Wolf, Rübsamen-Waigmann, Strebhardt: "Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain." in: Oncogene, Vol. 8, Issue 12, pp. 3433-40, 1993

Lapsys, Layfield, Baker, Callen, Sutherland, Abedinia, Nixon, Mattick: "Chromosomal location of the human transketolase gene." in: Cytogenetics and cell genetics, Vol. 61, Issue 4, pp. 274-5, 1993

Abedinia, Layfield, Jones, Nixon, Mattick: "Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase." in: Biochemical and biophysical research communications, Vol. 183, Issue 3, pp. 1159-66, 1992

Images

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling References for anti-DDR2 Antibody (ABIN359956) back to top
Supplier Images
 image for anti-DDR2 antibody (Discoidin Domain Receptor tyrosine Kinase 2) (AA 304-320) (ABIN359956) anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 297-327), (AA 304-320) antibody