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DDR2 antibody (AA 290-320)

DDR2 Reactivity: Human WB Host: Mouse Monoclonal 484CT5-5-4 unconjugated
Catalog No. ABIN1539910
  • Target See all DDR2 Antibodies
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Binding Specificity
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-320
    Reactivity
    • 47
    • 25
    • 2
    • 1
    Human
    Host
    • 54
    • 6
    Mouse
    Clonality
    • 54
    • 6
    Monoclonal
    Conjugate
    • 29
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDR2 antibody is un-conjugated
    Application
    • 46
    • 39
    • 21
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogen
    This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.
    Clone
    484CT5-5-4
    Isotype
    IgG1
    Top Product
    Discover our top product DDR2 Primary Antibody
  • Application Notes
    IHC: 1:200. WB: 1:100~1600
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    DDR2 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Alternative Name
    DDR2 (DDR2 Products)
    Synonyms
    MIG20a antibody, NTRKR3 antibody, TKT antibody, TYRO10 antibody, AW495251 antibody, Ntrkr3 antibody, tyro10 antibody, DDR2 antibody, Tyro10 antibody, ddr2 antibody, si:ch211-193c2.1 antibody, discoidin domain receptor tyrosine kinase 2 antibody, discoidin domain receptor family, member 2 antibody, discoidin domain receptor family, member 2, like antibody, DDR2 antibody, Ddr2 antibody, ddr2l antibody
    Background
    Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq].
    Molecular Weight
    96736
    Gene ID
    4921
    NCBI Accession
    NP_001014796, NP_006173
    UniProt
    Q16832
    Pathways
    RTK Signaling
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