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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||7 Antibodies|
|Flow Cytometry (FACS)||18 Antibodies|
|Immunocytochemistry (ICC)||9 Antibodies|
|Immunofluorescence (IF)||22 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||2 Antibodies|
|Immunohistochemistry (IHC)||51 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||24 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Western Blotting (WB)||107 Antibodies|
|Antigen||EPH Receptor B2 (EPHB2) Antibodies|
|Epitope||Internal Region Alternatives|
|Conjugate||This EPH Receptor B2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-EPH Receptor B2 AntibodyTarget Details EPH Receptor B2 Application Details Handling References for anti-EPH Receptor B2 Antibody (ABIN375195) Images
|Specificity||This antibody reacts to EPHB2.|
Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.
|Purification||ammonium sulphate precipitation followed by antigen affinity chromatography|
|Immunogen||Peptide with sequence C-QKDRNHRPKFGQ, from the internal region of the protein sequence|
Target Details EPH Receptor B2Product Details anti-EPH Receptor B2 Antibody Application Details Handling References for anti-EPH Receptor B2 Antibody (ABIN375195) Images back to top
|Alternative Name||EPHB2 (EPHB2 Antibody Abstract)|
|Background||Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: DRT, DRT, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, HEK5, NY-REN-47, Receptor protein-tyrosine kinase HEK5, Renal carcinoma antigen NY-REN-47, TYRO5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3|
Application DetailsProduct Details anti-EPH Receptor B2 Antibody Target Details EPH Receptor B2 Handling References for anti-EPH Receptor B2 Antibody (ABIN375195) Images back to top
ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-EPH Receptor B2 Antibody Target Details EPH Receptor B2 Application Details References for anti-EPH Receptor B2 Antibody (ABIN375195) Images back to top
|Buffer||Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-EPH Receptor B2 Antibody (ABIN375195)Product Details anti-EPH Receptor B2 Antibody Target Details EPH Receptor B2 Application Details Handling Images back to top
Cramer, Cerretti, Siddiqui: "EphB2 regulates axonal growth at the midline in the developing auditory brainstem." in: Developmental biology, Vol. 295, Issue 1, pp. 76-89, 2006 (PubMed).
ImagesProduct Details anti-EPH Receptor B2 Antibody Target Details EPH Receptor B2 Application Details Handling References for anti-EPH Receptor B2 Antibody (ABIN375195) back to top