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anti-Human FGF23 antibody for Enzyme Immunoassay

Recommended FGF23 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor 23 (FGF23) Antibodies
  • ADHR
  • FGF23
  • FGFN
  • HPDR2
  • HYPF
  • PHPTC
Epitope
Internal Region
25
8
7
6
5
4
3
2
1
1
1
Reactivity
Human
67
27
20
Host
Goat
50
26
18
Clonality
Polyclonal
Conjugate
This FGF23 antibody is un-conjugated
9
8
4
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
65
63
9
7
6
6
5
2
1
1
1
1
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Catalog No. ABIN375198
$ 379.50
Plus shipping costs $45.00

Top referenced anti-FGF23 antibody for Enzyme Immunoassay

Similar anti-FGF23 Antibodies

Application / Reactivity Human
ELISA 45 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Functional Studies (Func) 2 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 46 Antibodies

General

Antigen Fibroblast Growth Factor 23 (FGF23) Antibodies
Epitope Internal Region
(25), (8), (7), (6), (5), (4), (3), (2), (1), (1), (1)
Reactivity Human
(67), (27), (20)
Host Goat
(50), (26), (18)
Clonality
Polyclonal
Conjugate This FGF23 antibody is un-conjugated
(9), (8), (4), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(65), (63), (9), (7), (6), (6), (5), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-FGF23 Antibody

Target Details FGF23 Application Details Handling References for anti-FGF23 Antibody (ABIN375198) Images
Sequence C-RHTRSAEDDS ERD
Specificity This antibody recognizes FGF23.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography
Immunogen Synthetic peptide from the internal region of Human FGF23 (NP_065689.1) Genename: FGF23

Target Details FGF23

Product Details anti-FGF23 Antibody Application Details Handling References for anti-FGF23 Antibody (ABIN375198) Images back to top
Antigen
Alternative Name FGF23 (FGF23 Antibody Abstract)
Background Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) [MIM:193100]. ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC) [MIM:211900]. HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.Synonyms: FGF-23, Fibroblast growth factor 23, HYPF, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor
Molecular Weight 27.9 kDa (NP_065689.1).
Gene ID 8074
NCBI Accession NP_065689
UniProt Q9GZV9
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGF23 Antibody Target Details FGF23 Handling References for anti-FGF23 Antibody (ABIN375198) Images back to top
Application Notes ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FGF23 Antibody Target Details FGF23 Application Details References for anti-FGF23 Antibody (ABIN375198) Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-FGF23 Antibody (ABIN375198)

Product Details anti-FGF23 Antibody Target Details FGF23 Application Details Handling Images back to top
Background publications

Tang, Wang, Xu, Zhou, Jin, Wang, Gao: "Autocrine/paracrine action of vitamin D on FGF23 expression in cultured rat osteoblasts." in: Calcified tissue international, Vol. 86, Issue 5, pp. 404-10, 2010

Images

Product Details anti-FGF23 Antibody Target Details FGF23 Application Details Handling References for anti-FGF23 Antibody (ABIN375198) back to top
Supplier Images
 image for anti-FGF23 antibody (Fibroblast Growth Factor 23) (Internal Region) (ABIN375198) anti-Fibroblast Growth Factor 23 (FGF23) (Internal Region) antibody