anti-Human FGFR1 antibody for Enzyme Immunoassay

Recommended FGFR1 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies
  • FGFR
  • fgfr
  • X1FGFR
  • XFGFR-1
  • XFGFRA2
  • bfgfr
  • cek
  • fgfr1
  • flg
  • flt-2
  • flt2
  • kal2
  • ogd
  • xfgfr1
  • CG7223
  • CT22273
  • CT39172
  • DFGF-R1
  • DFGF-R2
  • DFR-1
  • DFR1
  • DFR1/DFGF-R2
  • DPR3
  • DTRK(FR1)
  • Dfr-1
  • Dfr1
  • DmHD-38
  • Dmel\\CG7223
  • Dtk1
  • EMS2
  • FGF-R2
  • FGFR2
  • FR1
  • Fr1
  • HD-38
  • HTL/FGFR1
  • Htl
  • Tk1
  • dtk1
  • i100
  • i150
  • i79
  • j372
  • cd331
  • fgfbr
  • fgfr-1
  • hbgfr
  • n-sam
  • ach
  • cd333
  • cek2
  • fgfr-3
  • hsfgfr3ex
  • jtk4
  • BFGFR
  • CD331
  • CEK
  • FGFBR
  • FGFR-1
  • FLG
  • FLT-2
  • FLT2
  • HBGFR
  • HH2
  • KAL2
  • N-SAM
  • OGD
  • bFGF-R-1
  • AW208770
  • Eask
  • Fgfr-1
  • Flt-2
  • Hspy
  • FLG-1
  • FGFRI
  • x1fgfr
  • cb231
  • sb:cb231
  • fibroblast growth factor receptor
  • fibroblast growth factor receptor 1
  • basic fibroblast growth factor receptor 1
  • heartless
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
  • Fibroblast growth factor receptor 1
  • fibroblast growth factor receptor 1a
  • FGFR
  • fgfr
  • fgfr1-a
  • CpipJ_CPIJ005849
  • htl
  • fgfr1
  • fgfr3
  • FGFR1
  • Fgfr1
  • fgfr1-b
  • fgfr1a
Epitope
pTyr766
62
59
56
52
40
37
37
36
34
14
12
12
12
11
10
10
10
10
10
9
9
9
8
8
8
6
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
623
284
222
21
14
14
11
11
7
6
4
4
2
2
2
1
1
Host
Rabbit
421
178
35
Clonality
Polyclonal
Conjugate
This FGFR1 antibody is un-conjugated
34
31
28
23
19
19
9
9
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
525
241
169
110
94
77
66
52
48
22
18
9
8
4
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN358128
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN951300 EIA WB Rabbit Ig Tyr307 Log in to see Polyclonal 4
1 ABIN359853 EIA WB Rabbit Ig Tyr154 Log in to see Polyclonal 5
1 ABIN358279 EIA Rabbit Ig pTyr307 Log in to see Polyclonal 5
1 ABIN5610933 EIA WB Rabbit Ig Fraction Tyr766 Log in to see Polyclonal
1 ABIN5610934 EIA WB Rabbit Ig Fraction Tyr653 Log in to see Polyclonal
1 ABIN5610935 EIA WB Rabbit Ig Fraction Tyr463 Log in to see Polyclonal
1 ABIN614919 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal
1 ABIN1107219 EIA WB Mouse IgG2b Log in to see 3D4F7 3
1 ABIN5555595 EIA WB Goat Internal Region Log in to see Polyclonal

General

Antigen Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies
Epitope pTyr766
(62), (59), (56), (52), (40), (37), (37), (36), (34), (14), (12), (12), (12), (11), (10), (10), (10), (10), (10), (9), (9), (9), (8), (8), (8), (6), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(623), (284), (222), (21), (14), (14), (11), (11), (7), (6), (4), (4), (2), (2), (2), (1), (1)
Host Rabbit
(421), (178), (35)
Clonality
Polyclonal
Conjugate This FGFR1 antibody is un-conjugated
(34), (31), (28), (23), (19), (19), (9), (9), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(525), (241), (169), (110), (94), (77), (66), (52), (48), (22), (18), (9), (8), (4), (2), (1), (1)
Pubmed 6 references available
Supplier Log in to see

Product Details anti-FGFR1 Antibody

Target Details FGFR1 Application Details Handling ProductDetails: References for anti-FGFR1 antibody (ABIN358128) Images
Specificity This antibody detects FGFR pTyr766.
Purification Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr766 of Human FGFR. Genename: FGFR1
Isotype Ig

Target Details FGFR1

Product Details anti-FGFR1 Antibody Application Details Handling ProductDetails: References for anti-FGFR1 antibody (ABIN358128) Images back to top
Antigen
Alternative Name FGFR1 (FGFR1 Antibody Abstract)
Background FGFR is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1
Molecular Weight 91868 Da
Gene ID 2260, 9606
UniProt P11362
Research Area Cancer, Growth Factors, Tyrosine Kinases, Angiogenesis, Cytokines, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance

Application Details

Product Details anti-FGFR1 Antibody Target Details FGFR1 Handling ProductDetails: References for anti-FGFR1 antibody (ABIN358128) Images back to top
Application Notes ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details ProductDetails: References for anti-FGFR1 antibody (ABIN358128) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-FGFR1 antibody (ABIN358128)

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details Handling Images back to top
Background publications

Ng, Boucher, Koh, Sastry, Chase, Lakshmipathy, Choong, Yang, Vemuri, Rao, Tanavde et al.: "PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in ..." in: Blood, Vol. 112, Issue 2, pp. 295-307, 2008

Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, 2004

Ibrahimi, Zhang, Hrstka, Mohammadi, Linhardt: "Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly." in: Biochemistry, Vol. 43, Issue 16, pp. 4724-30, 2004

Sato, Katsumata, Kagami, Hasegawa, Hori, Kawakita, Minowada, Shimotsuka, Shishiba, Yokozawa, Yasuda, Nagasaki, Hasegawa, Hasegawa, Tachibana, Naiki, Horikawa, Tanaka, Ogata: "Clinical assessment and mutation analysis of Kallmann syndrome 1 (KAL1) and fibroblast growth factor receptor 1 (FGFR1, or KAL2) in five families and 18 sporadic patients." in: The Journal of clinical endocrinology and metabolism, Vol. 89, Issue 3, pp. 1079-88, 2004

Lundin, Rönnstrand, Cross, Hellberg, Lindahl, Claesson-Welsh: "Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin." in: Experimental cell research, Vol. 287, Issue 1, pp. 190-8, 2003

Jiao, Greendorfer, Zhang, Zinn, Diglio, Thompson: "Alternatively spliced FGFR-1 isoform signaling differentially modulates endothelial cell responses to peroxynitrite." in: Archives of biochemistry and biophysics, Vol. 410, Issue 2, pp. 187-200, 2003

Images

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details Handling ProductDetails: References for anti-FGFR1 antibody (ABIN358128) back to top
Supplier Images
 image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibody (ABIN358128) anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibody
 image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibody (ABIN358128) anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibody (Image 2)
 image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibody (ABIN358128) anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (pTyr766) antibody (Image 3)