anti-Human FGFR4 antibody for Enzyme Immunoassay

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Reactivity
Human
207
56
45
3
3
Host
Rabbit
126
69
27
1
Clonality
Polyclonal
Conjugate
This FGFR4 antibody is un-conjugated
8
8
7
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
155
97
55
48
35
29
13
9
9
5
4
3
2
2
1
1
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Catalog No. ABIN359860
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552242 EIA IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
1 ABIN5610950 EIA IHC (p) WB Mouse IgG1 Log in to see 53CT32-19-3
1 ABIN614490 EIA IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2
1 ABIN1106283 EIA IF WB Mouse IgG1 Log in to see 7H1
1 ABIN2717942 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Reactivity Human
(207), (56), (45), (3), (3)
Host Rabbit
(126), (69), (27), (1)
Clonality
Polyclonal
Conjugate This FGFR4 antibody is un-conjugated
(8), (8), (7), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(155), (97), (55), (48), (35), (29), (13), (9), (9), (5), (4), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling References for anti-FGFR4 antibody (ABIN359860) Images
Specificity This antibody reacts to FGFR4.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with recombinant human FGFR4 protein.
Isotype Ig

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling References for anti-FGFR4 antibody (ABIN359860) Images back to top
Antigen
Alternative Name CD334 / FGFR4 (FGFR4 Antibody Abstract)
Background FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for family members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.Synonyms: FGFR-4, Fibroblast growth factor receptor 4, JTK2, TKF
Gene ID 2264, 9606
UniProt P22455
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling References for anti-FGFR4 antibody (ABIN359860) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details References for anti-FGFR4 antibody (ABIN359860) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-FGFR4 antibody (ABIN359860)

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling Images back to top
Background publications

Jézéquel, Campion, Joalland, Millour, Dravet, Classe, Delecroix, Deporte, Fumoleau, Ricolleau: "G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis." in: British journal of cancer, Vol. 90, Issue 1, pp. 189-93, 2004

Qian, Sano, Asa, Yamada, Horiguchi, Tashiro, Li, Hirokawa, Kovacs, Ezzat: "Cytoplasmic expression of fibroblast growth factor receptor-4 in human pituitary adenomas: relation to tumor type, size, proliferation, and invasiveness." in: The Journal of clinical endocrinology and metabolism, Vol. 89, Issue 4, pp. 1904-11, 2004

Yu, Asa, Weigel, Ezzat: "Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 19597-602, 2003

Becker, Nieters, Chang-Claude: "The fibroblast growth factor receptor gene Arg388 allele is not associated with early lymph node metastasis of breast cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 12, Issue 6, pp. 582-3, 2003

Takenaka, Yasuno, Kishimoto: "Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin." in: Archives of dermatological research, Vol. 294, Issue 7, pp. 331-8, 2002

Images

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling References for anti-FGFR4 antibody (ABIN359860) back to top
Supplier Images
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibody (ABIN359860) Western blot analysis of FGFR4 (arrow) using rabbit polyclonal FGFR4 Antibody.293 cel...