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anti-Rat (Rattus) FGFR4 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • cd334
  • CD334
  • etID309818.21
  • Fgfr-4
  • fgfr-4
  • fgfr-4c
  • fgfr4
  • FGFR4
  • JTK2
  • jtk2
  • tkf
  • TKF
  • wu:fc13h10
  • XFGFR-4
  • XFGFR-4a
  • xfgfr4
  • zgc:111935
Epitope
AA 40-90
23
13
10
7
7
7
6
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
169
42
34
2
2
1
Host
Rabbit
105
67
7
1
Clonality
Polyclonal
Conjugate
This FGFR4 antibody is un-conjugated
7
6
6
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
139
84
44
30
27
22
10
7
6
5
5
1
1
Supplier
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Catalog No. ABIN671766
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN897152 IF (p) Alexa Fluor 350 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN897153 IF (p) Alexa Fluor 647 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN897154 IF (p) Alexa Fluor 555 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN897151 IF (p) Alexa Fluor 488 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN671771 IF (p) Cy5.5 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN671770 IF (p) Cy5 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN671769 IF (p) Cy3 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN671773 IF (p) FITC Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN671772 IF (p) Cy7 Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008846439 ABIN2808609 IF (p) Alexa Fluor 594 Rabbit IgG AA 40-90 Log in to see Polyclonal

Similar anti-FGFR4 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 14 Antibodies 17 Antibodies 80 Antibodies
Immunofluorescence (IF) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 3 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 5 Antibodies
Immunoprecipitation (IP) 4 Antibodies 4 Antibodies
Western Blotting (WB) 22 Antibodies 28 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 27 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Epitope AA 40-90
(23), (13), (10), (7), (7), (7), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(169), (42), (34), (2), (2), (1)
Host Rabbit
(105), (67), (7), (1)
Clonality
Polyclonal
Conjugate This FGFR4 antibody is un-conjugated
(7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(139), (84), (44), (30), (27), (22), (10), (7), (6), (5), (5), (1), (1)
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Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human FGFR4
Isotype IgG

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name FGFR4/CD334 (FGFR4 Antibody Abstract)
Background

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes SRC-dependent phosphorylation of the matrix protease MMP14 and its lysosomal degradation. FGFR4 signaling is down-regulated by receptor internalization and degradation, MMP14 promotes internalization and degradation of FGFR4. Mutations that lead to constitutive kinase activation or impair normal FGFR4 inactivation lead to aberrant signaling.

Subcellular location: Extracellular


Synonyms: TKF, JTK2, CD334, Fibroblast growth factor receptor 4, FGFR-4, FGFR4
Gene ID 2264
UniProt P22455
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (AA 40-90) (ABIN671766) Formalin-fixed and paraffin embedded rat brain labeled Anti-FGFR4 Polyclonal Antibody...
Immunohistochemistry (IHC) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (AA 40-90) (ABIN671766) Formalin-fixed and paraffin embedded human cervical carcinoma labeled Anti-FGFR4 Poly...