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anti-Human FLT3 antibody for Enzyme Immunoassay

Recommended FLT3 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
  • B230315G04
  • CD135
  • FLK-2
  • Flk-2
  • FLK2
  • Flk2
  • Flt-3
  • FLT3
  • Ly72
  • STK1
  • wmfl
Epitope
N-Term
42
30
27
20
19
15
14
13
10
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
277
128
40
1
1
1
Host
Rabbit
244
59
20
1
Clonality
Polyclonal
Conjugate
This FLT3 antibody is un-conjugated
20
18
16
13
10
6
4
4
4
4
4
4
4
4
4
4
2
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
163
121
76
46
46
45
20
15
10
3
2
2
2
1
1
Supplier
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Catalog No. ABIN1449983
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008867729 ABIN359869 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
0.0008867729 ABIN359868 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
0.0008867729 ABIN317712 EIA WB Rabbit Log in to see Polyclonal

Top referenced anti-FLT3 antibody for Enzyme Immunoassay

Similar anti-FLT3 Antibodies

Application / Reactivity Mouse (Murine) Human
Blocking Reagent (BR) 2 Antibodies
ELISA 44 Antibodies 106 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Flow Cytometry (FACS) 16 Antibodies 61 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 35 Antibodies
Immunohistochemistry (IHC) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Western Blotting (WB) 76 Antibodies
ELISA (Capture) 1 Antibodies

General

Antigen Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
Epitope N-Term
(42), (30), (27), (20), (19), (15), (14), (13), (10), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(277), (128), (40), (1), (1), (1)
Host Rabbit
(244), (59), (20), (1)
Clonality
Polyclonal
Conjugate This FLT3 antibody is un-conjugated
(20), (18), (16), (13), (10), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(163), (121), (76), (46), (46), (45), (20), (15), (10), (3), (2), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-FLT3 Antibody

Target Details FLT3 Application Details Handling References for anti-FLT3 Antibody (ABIN1449983) Images
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Affinity chromatography purified via peptide column
Immunogen 18 amino acid synthetic peptide near the center of Human FLT3
Isotype IgG

Target Details FLT3

Product Details anti-FLT3 Antibody Application Details Handling References for anti-FLT3 Antibody (ABIN1449983) Images back to top
Antigen
Alternative Name CD135 / FLT3 (FLT3 Antibody Abstract)
Background FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity.Synonyms: FL cytokine receptor, STK1, Stem cell tyrosine kinase 1, Tyrosine-protein kinase receptor FLT3
Molecular Weight 109 kDa
Gene ID 2322
NCBI Accession NP_004110
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-FLT3 Antibody Target Details FLT3 Handling References for anti-FLT3 Antibody (ABIN1449983) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details References for anti-FLT3 Antibody (ABIN1449983) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-FLT3 Antibody (ABIN1449983)

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling Images back to top
Background publications

Takahashi: "Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications." in: Journal of hematology & oncology, Vol. 4, pp. 13, 2011

Manno: "Measurement of the digit lengths and the anogenital distance in mice." in: Physiology & behavior, Vol. 93, Issue 1-2, pp. 364-8, 2008

Rosnet, Schiff, Pébusque, Marchetto, Tonnelle, Toiron, Birg, Birnbaum: "Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells." in: Blood, Vol. 82, Issue 4, pp. 1110-9, 1993

Images

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling References for anti-FLT3 Antibody (ABIN1449983) back to top
Supplier Images
Western Blotting (WB) image for anti-FLT3 antibody (Fms-Related tyrosine Kinase 3) (N-Term) (ABIN1449983) Western blot analysis of FLT3 in 3T3 cell lysate with FLT3 antibody at (A) 1 and (B)2...