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anti-Mouse (Murine) Galectin 3 antibody for Blocking Reagent

Recommended Galectin 3 Antibody (supplied by: Log in to see )

Antigen
Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antibodies
  • CBP 35
  • CBP35
  • gal-3
  • Gal-3
  • GAL3
  • gal3
  • galactoside-binding
  • GALBP
  • Galectin-3
  • galectin-3
  • GALIG
  • GBP
  • L-34
  • L31
  • lectin
  • leg3
  • LGALS2
  • LGALS3
  • Mac-2
  • MAC2
  • MGC52947
  • MGC75803
  • soluble
Epitope
AA 151-251
52
20
17
16
16
15
11
10
8
7
6
6
5
5
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
311
125
57
4
3
3
2
1
Host
Mouse
209
135
32
14
Clonality
Monoclonal
Conjugate
This Galectin 3 antibody is conjugated to PE
33
21
15
14
10
10
2
2
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
265
172
110
73
54
46
20
15
14
12
10
6
6
4
2
1
1
1
1
1
1
1
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Catalog No. ABIN2663838
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Top referenced anti-Galectin 3 antibody for Blocking Reagent

Similar anti-Galectin 3 Antibodies

Application / Reactivity Mouse (Murine) Human
Blocking Reagent (BR) 1 Antibodies 1 Antibodies
ELISA 57 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 26 Antibodies
Functional Studies (Func) 2 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 20 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 33 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 88 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Cellular Assay (CA) 1 Antibodies

General

Antigen Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antibodies
Epitope AA 151-251
(52), (20), (17), (16), (16), (15), (11), (10), (8), (7), (6), (6), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(311), (125), (57), (4), (3), (3), (2), (1)
Host Mouse
(209), (135), (32), (14)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Galectin 3 antibody is conjugated to PE
(33), (21), (15), (14), (10), (10), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
(265), (172), (110), (73), (54), (46), (20), (15), (14), (12), (10), (6), (6), (4), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-Galectin 3 Antibody

Target Details Galectin 3 Application Details Handling References for anti-Galectin 3 Antibody (ABIN2663838) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone Gal397
Isotype IgG1 kappa

Target Details Galectin 3

Product Details anti-Galectin 3 Antibody Application Details Handling References for anti-Galectin 3 Antibody (ABIN2663838) Images back to top
Antigen
Alternative Name Mac-2 (LGALS3 Antibody Abstract)
Background Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.
Pathways RTK Signaling

Application Details

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Handling References for anti-Galectin 3 Antibody (ABIN2663838) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details References for anti-Galectin 3 Antibody (ABIN2663838) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-Galectin 3 Antibody (ABIN2663838)

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details Handling Images back to top
Background publications

Takenaka, Fukumori, Yoshii, Oka, Inohara, Kim, Bresalier, Raz: "Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs." in: Molecular and cellular biology, Vol. 24, Issue 10, pp. 4395-406, 2004

Reljic, Crawford, Challacombe, Ivanyi: "Mouse monoclonal IgA binds to the galectin-3/Mac-2 lectin from mouse macrophage cell lines." in: Immunology letters, Vol. 93, Issue 1, pp. 51-6, 2004

Joo, Goedegebuure, Sadanaga, Nagoshi, von Bernstorff, Eberlein: "Expression and function of galectin-3, a beta-galactoside-binding protein in activated T lymphocytes." in: Journal of leukocyte biology, Vol. 69, Issue 4, pp. 555-64, 2001

Kim, Lin, Biliran, Raz: "Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells." in: Cancer research, Vol. 59, Issue 16, pp. 4148-54, 1999

Images

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details Handling References for anti-Galectin 3 Antibody (ABIN2663838) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Galectin 3 antibody (Lectin, Galactoside-Binding, Soluble, 3) (AA 151-251) (PE) (ABIN2663838) anti-Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) (AA 151-251) antibody (PE)