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anti-Mouse (Murine) Galectin 3 antibody for Functional Studies

Recommended Galectin 3 Antibody (supplied by: Log in to see )

Antigen
Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antibodies
  • CBP 35
  • CBP35
  • gal-3
  • Gal-3
  • GAL3
  • gal3
  • galactoside-binding
  • GALBP
  • Galectin-3
  • galectin-3
  • GALIG
  • GBP
  • L-34
  • L31
  • lectin
  • leg3
  • LGALS2
  • LGALS3
  • Mac-2
  • MAC2
  • MGC52947
  • MGC75803
  • soluble
Reactivity
Human, Mouse (Murine)
311
125
57
4
3
3
2
1
Host
Mouse
209
135
32
14
Clonality
Monoclonal
Conjugate
This Galectin 3 antibody is un-conjugated
33
21
16
14
10
10
2
2
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
264
172
111
72
55
46
19
16
14
12
9
6
6
3
2
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1107301
$ 489.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087864255 ABIN2142263 Func FACS Rat IgG2a kappa Log in to see M3-38

Top referenced anti-Galectin 3 antibody for Functional Studies

  • Human Monoclonal Galectin 3 Primary Antibody for Func, EIA - ABIN1107301 (3 Publications): Feilchenfeldt, Tötsch, Sheu, Robert, Spiliopoulos, Frilling, Schmid, Meier: Expression of galectin-3 in normal and malignant thyroid tissue by quantitative PCR and immunohistochemistry. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003 (PubMed)

Similar anti-Galectin 3 Antibodies

Application / Reactivity Mouse (Murine) Human
Blocking Reagent (BR) 1 Antibodies 1 Antibodies
ELISA 57 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 26 Antibodies
Functional Studies (Func) 2 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 20 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 33 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 88 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Cellular Assay (CA) 1 Antibodies

General

Antigen Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antibodies
Reactivity Human, Mouse (Murine)
(311), (125), (57), (4), (3), (3), (2), (1)
Host Mouse
(209), (135), (32), (14)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Galectin 3 antibody is un-conjugated
(33), (21), (16), (14), (10), (10), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(264), (172), (111), (72), (55), (46), (19), (16), (14), (12), (9), (6), (6), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Galectin 3 Antibody

Target Details Galectin 3 Application Details Handling References for anti-Galectin 3 Antibody (ABIN1107301) Images
Specificity This antibody reacts with galectin-3, a 30 kDa protein.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein G
Clone B2C10
Isotype IgG1

Target Details Galectin 3

Product Details anti-Galectin 3 Antibody Application Details Handling References for anti-Galectin 3 Antibody (ABIN1107301) Images back to top
Antigen
Alternative Name Galectin-3 (LGALS3 Antibody Abstract)
Background Galectin-3 is a member of the galectin family. The protein is composed of three domains: a small amino-terminal domain, a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal domain containing repeating elements. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. The expression is also affected by neoplastic transformation: up-regulated in certain types of lymphomas and thyroid carcinoma, while down-regulated in other types of malignancies, such as colon, breast, ovarian and uterine carcinomas. Galectin-3 has been shown to function through both intracellular and extracellular actions. Related to its intracellular functions, galectin-3 has been identified as a component of heterogeneous nuclear ribonuclear protein (hnRNP), a factor in pre-mRNA splicing, and has been found to control cell cycle and prevent T cell apoptosis. On the other hand, this protein has also been demonstrated to function as extracellular molecule in activating various types of cells, including monocytes/macrophages, mast cells, neutrophils and lymphocytes. Galectin-3 has been shown to mediate cell-cell and cell-extracellular matrix interactions.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2
Gene ID 3958
NCBI Accession NP_002297
UniProt P17931
Research Area Neurology
Pathways RTK Signaling

Application Details

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Handling References for anti-Galectin 3 Antibody (ABIN1107301) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details References for anti-Galectin 3 Antibody (ABIN1107301) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.1 % bovine serum albumin
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-Galectin 3 Antibody (ABIN1107301)

Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details Handling Images back to top
Background publications

Feilchenfeldt, Tötsch, Sheu, Robert, Spiliopoulos, Frilling, Schmid, Meier: "Expression of galectin-3 in normal and malignant thyroid tissue by quantitative PCR and immunohistochemistry." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 16, Issue 11, pp. 1117-23, 2003

Sano, Hsu, Yu, Apgar, Kuwabara, Yamanaka, Hirashima, Liu: "Human galectin-3 is a novel chemoattractant for monocytes and macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 4, pp. 2156-64, 2000

Liu, Hsu, Zuberi, Hill, Shenhav, Kuwabara, Chen: "Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains." in: Biochemistry, Vol. 35, Issue 19, pp. 6073-9, 1996