anti-Human INSRR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended INSRR Antibody (supplied by: Log in to see )

Antigen
Insulin Receptor-Related Receptor (INSRR) Antibodies
  • INSRR
  • MGC68585
  • Insrr
  • IRR
  • Irr
  • Sirr
  • insulin receptor-related receptor
  • insulin receptor
  • INSRR
  • insrr
  • LOC100338576
  • Insrr
  • Insr
Epitope
AA 16-47, N-Term
21
16
12
8
8
7
4
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
98
49
25
Host
Rabbit
73
31
Clonality
Polyclonal
Conjugate
This INSRR antibody is un-conjugated
5
5
5
4
4
4
4
4
4
4
4
3
3
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
63
44
23
19
13
11
2
2
2
2
1
Options
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Catalog No. ABIN392004
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN359888 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 4
1 ABIN359889 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 4
1 ABIN392005 IHC (p) WB Rabbit Ig AA 1256-1287, C-Term Log in to see Polyclonal 1
1 ABIN598764 IHC (p) ELISA WB Mouse IgG1, kappa AA 651-760 Log in to see 6E6
1 ABIN902843 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN561505 IHC (p) ELISA WB Mouse IgG1 kappa AA 651-760, partial Log in to see 6E6
1 ABIN4326008 IHC IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN902834 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN872418 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN1840518 IHC (p) WB Rabbit AA 16-47 Log in to see Polyclonal
1 ABIN1840519 IHC (p) WB Rabbit AA 1256-1287 Log in to see Polyclonal

General

Antigen Insulin Receptor-Related Receptor (INSRR) Antibodies
Epitope AA 16-47, N-Term
(21), (16), (12), (8), (8), (7), (4), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(98), (49), (25)
Host Rabbit
(73), (31)
Clonality (Clone)
Polyclonal   ( )
Conjugate This INSRR antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(63), (44), (23), (19), (13), (11), (2), (2), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-INSRR Antibody

Target Details INSRR Application Details Handling References for anti-INSRR antibody (ABIN392004) Images
Specificity This Insulin Receptor R Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25~55 amino acids from the N-terminal region of human INSRR.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This Insulin Receptor R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-47 AA from the N-terminal region of human Insulin Receptor R.
Clone RB1421
Isotype Ig

Target Details INSRR

Product Details anti-INSRR Antibody Application Details Handling References for anti-INSRR antibody (ABIN392004) Images back to top
Antigen
Alternative Name INSRR (Insulin Receptor R) (INSRR Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Synonyms: insulin receptor-related receptor
Molecular Weight 143719 DA
Gene ID 3645
UniProt P14616
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways RTK Signaling

Application Details

Product Details anti-INSRR Antibody Target Details INSRR Handling References for anti-INSRR antibody (ABIN392004) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-INSRR Antibody Target Details INSRR Application Details References for anti-INSRR antibody (ABIN392004) Images back to top
Format Liquid
Concentration 1.64 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-INSRR antibody (ABIN392004)

Product Details anti-INSRR Antibody Target Details INSRR Application Details Handling Images back to top
Background publications

Shier, Watt: "Primary structure of a putative receptor for a ligand of the insulin family." in: The Journal of biological chemistry, Vol. 264, Issue 25, pp. 14605-8, 1989

Images

Product Details anti-INSRR Antibody Target Details INSRR Application Details Handling References for anti-INSRR antibody (ABIN392004) back to top
Supplier Images
Western Blotting (WB) image for anti-Insulin Receptor-Related Receptor (INSRR) (AA 16-47), (N-Term) antibody (ABIN392004) Western blot analysis of anti-INSRR Pab (ABIN392004) in mouse brain lysate. INSRR (ar...
Immunohistochemistry (IHC) image for anti-Insulin Receptor-Related Receptor (INSRR) (AA 16-47), (N-Term) antibody (ABIN392004) Formalin-fixed and paraffin-embedded human testis tissue reacted with INSRR antibody ...