anti-Mouse (Murine) KIT Ligand antibody for Immunohistochemistry (Frozen Sections)

Recommended KIT Ligand Antibody (supplied by: Log in to see )

Antigen
KIT Ligand (KITLG) Antibodies
  • Xkl-1
  • Xsl
  • Xsl-1
  • Xsl-2
  • steel
  • KITLG
  • SCF
  • kitl
  • kl-1
  • mgf
  • scf
  • FPH2
  • KL-1
  • Kitl
  • MGF
  • SF
  • SHEP7
  • Clo
  • Con
  • Gb
  • Kitlg
  • Mgf
  • SLF
  • Sl
  • blz
  • contrasted
  • 710-712
  • CSF
  • KITL
  • KIT ligand
  • kit ligand
  • kitlg
  • KITLG
  • Kitl
  • Kitlg
Epitope
AA 160-210
18
15
9
8
7
7
6
5
5
5
4
3
3
3
3
3
3
3
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
208
81
65
5
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
205
60
21
1
Clonality
Polyclonal
Conjugate
This KIT Ligand antibody is un-conjugated
35
13
10
9
9
7
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
234
148
49
36
30
28
24
23
15
12
11
9
4
3
3
2
2
1
1
1
1
1
1
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Catalog No. ABIN669936
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN669945 IHC (fro) IHC (p) WB HRP Rabbit IgG AA 160-210 Log in to see Polyclonal
1 ABIN669938 IHC (fro) IHC (p) WB Biotin Rabbit IgG AA 160-210 Log in to see Polyclonal

General

Antigen KIT Ligand (KITLG) Antibodies
Epitope AA 160-210
(18), (15), (9), (8), (7), (7), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(208), (81), (65), (5), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(205), (60), (21), (1)
Clonality
Polyclonal
Conjugate This KIT Ligand antibody is un-conjugated
(35), (13), (10), (9), (9), (7), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(234), (148), (49), (36), (30), (28), (24), (23), (15), (12), (11), (9), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-KIT Ligand Antibody

Target Details KIT Ligand Application Details Handling References for anti-KIT Ligand antibody (ABIN669936) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SCF
Isotype IgG

Target Details KIT Ligand

Product Details anti-KIT Ligand Antibody Application Details Handling References for anti-KIT Ligand antibody (ABIN669936) Images back to top
Antigen
Alternative Name SCF (KITLG Antibody Abstract)
Background

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

Subcellular location: Extracellular

Synonyms: SF, MGF, SCF, FPH2, KL-1, Kitl, SHEP7, Kit ligand, Mast cell growth factor, Stem cell factor, c-Kit ligand, KITLG

Gene ID 4254
UniProt P21583
Research Area Embryogenesis, Embryonic stem cells, Innate Immunity, Cytokines
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-KIT Ligand Antibody Target Details KIT Ligand Handling References for anti-KIT Ligand antibody (ABIN669936) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-KIT Ligand Antibody Target Details KIT Ligand Application Details References for anti-KIT Ligand antibody (ABIN669936) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-KIT Ligand antibody (ABIN669936)

Product Details anti-KIT Ligand Antibody Target Details KIT Ligand Application Details Handling Images back to top
Product cited in:

Lin, Tang, Cai, Wang, Li, Sui, Guo: "NPs/NPRs Signaling Pathways May Be Involved in Depression-Induced Loss of Gastric ICC by Decreasing the Production of mSCF." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149031, 2016

Wang, Wang, Li, Liu, Jiang, Li, Cao, Zhao, Wang, Luo: "Silencing stem cell factor attenuates stemness and inhibits migration of cancer stem cells derived from Lewis lung carcinoma cells." in: Tumour biology, Vol. 37, Issue 6, pp. 7213-27, 2016

Goldstein, Goss, Hatzistergos, Rangel, Seidler, Saur, Hare: "Adult c-Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons." in: The Journal of comparative neurology, 2014

Images

Product Details anti-KIT Ligand Antibody Target Details KIT Ligand Application Details Handling References for anti-KIT Ligand antibody (ABIN669936) back to top
Supplier Images
Immunofluorescence (IF) image for anti-KIT Ligand (KITLG) (AA 160-210) antibody (ABIN669936) Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-SCF Polyclon...
Immunohistochemistry (IHC) image for anti-KIT Ligand (KITLG) (AA 160-210) antibody (ABIN669936) Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-SCF Polyclon...
Immunofluorescence (IF) image for anti-KIT Ligand (KITLG) (AA 160-210) antibody (ABIN669936) Formalin-fixed and paraffin embedded rat spleen tissue labeled with Anti-SCF Polyclon...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-KIT Ligand (KITLG) (AA 160-210) antibody (ABIN669936) Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-SCF Polyclon...