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anti-Human Neuregulin 1 antibody for Flow Cytometry

Recommended Neuregulin 1 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 1 (NRG1) Antibodies
  • 6030402G23Rik
  • ARIA
  • D230005F13Rik
  • DKFZp459A1838
  • GGF
  • GGF2
  • GGFII
  • heregulin
  • HGL
  • Hgl
  • HPRG
  • HRG
  • HRG1
  • HRGA
  • HRGalpha
  • HRGP
  • MST131
  • NDF
  • NRG-1
  • NRG1
  • nrg1-A
  • pro-neuregulin-1
  • SMDF
  • THPH11
  • wu:fm70e01
Epitope
AA 198-229, Center
21
21
20
13
12
8
8
8
7
7
7
7
5
4
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
198
71
62
2
1
1
1
Host
Rabbit
194
42
Clonality
Polyclonal
Conjugate
This Neuregulin 1 antibody is un-conjugated
19
12
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
177
110
62
41
18
12
11
10
10
8
5
4
3
3
Supplier
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Catalog No. ABIN390160
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.30226976 ABIN2447249 FACS WB Rabbit Ig Fraction Center Log in to see Polyclonal
0.0010482287 ABIN960504 FACS IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
0.0010482287 ABIN1737531 FACS IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0010482287 ABIN1918552 FACS IHC ELISA WB FITC Rabbit IgG Internal Region Log in to see Polyclonal
0.0010482287 ABIN1918551 FACS IHC ELISA WB APC Rabbit IgG Internal Region Log in to see Polyclonal
0.0010482287 ABIN1918550 FACS IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Internal Region Log in to see Polyclonal
0.0010482287 ABIN1918553 FACS IHC ELISA WB PE Rabbit IgG Internal Region Log in to see Polyclonal
0.0010482287 ABIN2471930 FACS IHC ELISA WB Rabbit Center Log in to see Polyclonal
0.0010482287 ABIN1918554 FACS IHC ELISA WB HRP Rabbit IgG Internal Region Log in to see Polyclonal
0.0010482287 ABIN2313643 FACS IHC ELISA WB APC Rabbit IgG Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN2313656 FACS IHC ELISA WB PE Rabbit IgG Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN2313650 FACS IHC ELISA WB FITC Rabbit IgG Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN2313637 FACS IHC ELISA WB Rabbit IgG Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN2313647 FACS IHC ELISA WB Biotin Rabbit IgG Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN2313640 FACS IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Center, Internal Region Log in to see Polyclonal
0.0010482287 ABIN3031974 FACS IHC ELISA WB Rabbit Ig Fraction AA 198-229 Log in to see Polyclonal
0.0010482287 ABIN2280899 FACS IHC ELISA WB Rabbit Log in to see Polyclonal
0.0010482287 ABIN2794834 FACS IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal

Top referenced anti-Neuregulin 1 antibody for Flow Cytometry

Similar anti-Neuregulin 1 Antibodies

Application / Reactivity Human
Blocking Reagent (BR) 3 Antibodies
ELISA 91 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 19 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 57 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 34 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Neutralization (Neut) 8 Antibodies
Western Blotting (WB) 158 Antibodies

General

Antigen Neuregulin 1 (NRG1) Antibodies
Epitope AA 198-229, Center
(21), (21), (20), (13), (12), (8), (8), (8), (7), (7), (7), (7), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(198), (71), (62), (2), (1), (1), (1)
Host Rabbit
(194), (42)
Clonality (Clone)
Polyclonal   ( )
Conjugate This Neuregulin 1 antibody is un-conjugated
(19), (12), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(177), (110), (62), (41), (18), (12), (11), (10), (10), (8), (5), (4), (3), (3)
Pubmed 4 references available
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Product Details anti-Neuregulin 1 Antibody

Target Details Neuregulin 1 Application Details Handling References for anti-Neuregulin 1 Antibody (ABIN390160) Images
Specificity This NRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human NRG1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This NRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-229 AA from the Central region of human NRG1.
Clone RB01275-01276
Isotype Ig

Target Details Neuregulin 1

Product Details anti-Neuregulin 1 Antibody Application Details Handling References for anti-Neuregulin 1 Antibody (ABIN390160) Images back to top
Antigen
Alternative Name NRG1 (NRG1 Antibody Abstract)
Background Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains, and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
Molecular Weight 70260 DA
Gene ID 3084
UniProt Q02297
Research Area Stem Cells, Cell Structure, Cell Cycle, Neurology
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Handling References for anti-Neuregulin 1 Antibody (ABIN390160) Images back to top
Application Notes WB = 1:1000, FACS = 1:10-50, IHC (p) = 1:50-100
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details References for anti-Neuregulin 1 Antibody (ABIN390160) Images back to top
Format Liquid
Concentration 1.79 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-Neuregulin 1 Antibody (ABIN390160)

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Handling Images back to top
Product cited in:

Mondal, Schilling, Folger, Steibel, Buchnick, Zalman, Ireland, Meidan, Smith: "Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F??." in: Physiological genomics, Vol. 43, Issue 8, pp. 447-56, 2011

Background publications

Ritch, Carroll, Sontheimer: "Neuregulin-1 enhances motility and migration of human astrocytic glioma cells." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 20971-8, 2003

Vermeer, Einwalter, Moninger, Rokhlina, Kern, Zabner, Welsh: "Segregation of receptor and ligand regulates activation of epithelial growth factor receptor." in: Nature, Vol. 422, Issue 6929, pp. 322-6, 2003

Atlas, Cardillo, Mehmi, Zahedkargaran, Tang, Lupu: "Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo." in: Molecular cancer research : MCR, Vol. 1, Issue 3, pp. 165-75, 2003

Images

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Handling References for anti-Neuregulin 1 Antibody (ABIN390160) back to top
Supplier Images
Western Blotting (WB) image for anti-Neuregulin 1 antibody (NRG1) (AA 198-229) (ABIN390160) Western blot analysis of anti-NRG1 Antibody (Center) (ABIN390160) in SK-BR-3 cell lin...
Immunohistochemistry (IHC) image for anti-Neuregulin 1 antibody (NRG1) (AA 198-229) (ABIN390160) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Flow Cytometry (FACS) image for anti-Neuregulin 1 antibody (NRG1) (AA 198-229) (ABIN390160) Flow cytometric analysis of NCI-H460 cells using NRG1 Antibody (Center) (bottom histo...