anti-Rat (Rattus) Neuregulin 1 antibody for Immunohistochemistry (Frozen Sections)

Recommended Neuregulin 1 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 1 (NRG1) Antibodies
  • NRG1
  • wu:fm70e01
  • DKFZp459A1838
  • HPRG
  • HRGP
  • THPH11
  • HRG1
  • ARIA
  • GGF
  • GGF2
  • HGL
  • HRG
  • HRGA
  • MST131
  • NDF
  • SMDF
  • 6030402G23Rik
  • D230005F13Rik
  • GGFII
  • HRGalpha
  • Hgl
  • pro-neuregulin-1
  • NRG-1
  • heregulin
  • nrg1-A
  • neuregulin 1
  • histidine-rich glycoprotein
  • NRG1
  • nrg1
  • Nrg1
  • HRG
  • Hrg
Epitope
AA 617-636, C-Term
23
20
16
14
11
10
8
7
7
7
6
6
5
5
5
4
4
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
239
80
77
3
3
2
1
1
1
1
1
Host
Rabbit
203
69
Clonality
Polyclonal
Conjugate
This Neuregulin 1 antibody is un-conjugated
21
13
7
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
225
128
69
43
19
16
15
10
8
5
5
5
4
4
3
1
Options
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Catalog No. ABIN3044035
$ 200.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN264425 IHC (fro) IP WB Mouse IgG2a Extracellular Domain Log in to see 7D5 4
1 ABIN3031973 ICC IHC (fro) IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

General

Antigen Neuregulin 1 (NRG1) Antibodies
Epitope AA 617-636, C-Term
(23), (20), (16), (14), (11), (10), (8), (7), (7), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(239), (80), (77), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(203), (69)
Clonality
Polyclonal
Conjugate This Neuregulin 1 antibody is un-conjugated
(21), (13), (7), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(225), (128), (69), (43), (19), (16), (15), (10), (8), (5), (5), (5), (4), (4), (3), (1)
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Product Details anti-Neuregulin 1 Antibody

Target Details Neuregulin 1 Application Details Handling Images
Purpose Rabbit IgG polyclonal antibody for Pro-neuregulin-1, membrane-bound isoform(NRG1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Sequence RFSTQEEIQA RLSSVIANQD
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Pro-neuregulin-1, membrane-bound isoform(NRG1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: neuregulin 1
Protein Name: Pro-neuregulin-1, membrane-bound isoform
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human NRG1(617-636aa RFSTQEEIQARLSSVIANQD), different from the related rat and mouse sequences by one amino acids.
Isotype IgG

Target Details Neuregulin 1

Product Details anti-Neuregulin 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name NRG1 (NRG1 Antibody Abstract)
Background NRG1(Neuregulin 1), also known as ARIA, NDF or HRGA, is a protein that in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. By in situ hybridization of a tritium-labeled probe to human metaphase spreads, Orr-Urtreger et al.(1993) localized the NDF gene to 8p21-p12. In mouse embryos 14.5 days postcoitum, Orr-Urtreger et al.(1993) found that NDF expression is confined predominantly to the central and peripheral nervous systems, including the neuroepithelium that lines the lateral ventricles of the brain, the ventral horn of the spinal cord, and the intestinal as well as dorsal root ganglia.

Synonyms: Acetylcholine receptor inducing activity antibody|Acetylcholine receptor-inducing activity antibody|ARIA antibody|Breast cancer cell differentiation factor p45 antibody|GGF antibody|GGF2 antibody|Glial growth factor antibody|heregulin antibody|heregulin, alpha(45kD, ERBB2 p185-activator) antibody|HGL antibody|HRG antibody|HRG1 antibody|HRGA antibody|MST131 antibody|NDF antibody|Neu differentiation factor antibody|Neuregulin 1 antibody|neuregulin 1 type IV beta 1a antibody|neuregulin 1 type IV beta 3 antibody|Neuregulin-1 antibody|NRG 1 antibody|nrg1 antibody|NRG1_HUMAN antibody|OTTHUMP00000225398 antibody|OTTHUMP00000225419 antibody|OTTHUMP00000225420 antibody|OTTHUMP00000225421 antibody|OTTHUMP00000225422 antibody|OTTHUMP00000225477 antibody|OTTHUMP00000225545 antibody|OTTHUMP00000230603 antibody|OTTHUMP00000230605 antibody|Pro-NRG1 antibody|ProNRG1 antibody|Sensory and motor neuron-derived factor antibody|SMDF antibody
UniProt Q02297
Research Area Neurology, Glia marker
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation

Application Details

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Handling Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

Images

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody (ABIN3044035) Anti-NRG1 antibody, IHC(P) IHC(P): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody (ABIN3044035) Anti-NRG1 antibody, IHC(F) IHC(F): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody (ABIN3044035) Anti-NRG1 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue
Western Blotting (WB) image for anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody (ABIN3044035) Anti-NRG1 antibody, Western blotting Lane 1: Rat Spleen Tissue Lysate Lane 2: Rat Kid...
Immunohistochemistry (IHC) image for anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody (ABIN3044035) Anti-NRG1 antibody, ICC ICC: HELA Cell