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anti-Human Neuregulin 3 antibody for Western Blotting

Recommended Neuregulin 3 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 3 (NRG3) Antibodies
  • NRG3
  • HRG3
  • pro-NRG3
  • ska
  • RGD1559678
  • neuregulin 3
  • NRG3
  • nrg3
  • Nrg3
Epitope
AA 688-717, C-Term
16
15
11
2
2
2
2
1
1
1
1
1
Reactivity
Human
71
33
27
5
3
1
1
1
1
1
Host
Rabbit
56
18
Clonality
Polyclonal
Conjugate
This Neuregulin 3 antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
40
34
28
14
13
1
Options
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Catalog No. ABIN1881587
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1771314 ABIN253309 ELISA WB Goat C-Term Log in to see Polyclonal 1
3.1771314 ABIN2957693 IHC WB Rabbit Log in to see Polyclonal
3.1771314 ABIN3181485 ELISA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
3.1771314 ABIN2458866 ELISA WB Rabbit Log in to see Polyclonal
3.1771314 ABIN2466542 ELISA WB Goat C-Term Log in to see Polyclonal
3.1771314 ABIN1538560 WB Rabbit Ig AA 647-677, Center Log in to see Polyclonal
3.1771314 ABIN2564094 ELISA WB Goat IgG C-Term Log in to see Polyclonal
3.1771314 ABIN4892229 IHC IHC (p) WB Rabbit Log in to see Polyclonal
3.1771314 ABIN2434194 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
3.1771314 ABIN2432559 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2781935 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
1 ABIN374780 WB Goat C-Term Log in to see Polyclonal 1
1 ABIN190905 ELISA WB Goat C-Term Log in to see Polyclonal 1
1 ABIN303890 ELISA WB Goat AA 709-720 Log in to see Polyclonal
1 ABIN768921 IHC (p) WB Rabbit IgG AA 540-589 Log in to see Polyclonal
1 ABIN716156 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN5531713 IHC (p) WB Rabbit Ig Fraction AA 305-336 Log in to see Polyclonal
1 ABIN5531714 IHC (p) WB Rabbit Ig Fraction AA 688-717, C-Term Log in to see Polyclonal
1 ABIN716165 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN2322182 ELISA WB FITC Goat C-Term Log in to see Polyclonal

Top referenced anti-Neuregulin 3 antibody for Western Blotting

Similar anti-Neuregulin 3 Antibodies

Application / Reactivity Human
ELISA 39 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 25 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Western Blotting (WB) 32 Antibodies

General

Antigen Neuregulin 3 (NRG3) Antibodies
Epitope AA 688-717, C-Term
(16), (15), (11), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(71), (33), (27), (5), (3), (1), (1), (1), (1), (1)
Host Rabbit
(56), (18)
Clonality (Clone)
Polyclonal   ( )
Conjugate This Neuregulin 3 antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(40), (34), (28), (14), (13), (1)
Pubmed 2 references available
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Product Details anti-Neuregulin 3 Antibody

Target Details Neuregulin 3 Application Details Handling References for anti-Neuregulin 3 Antibody (ABIN1881587) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This NRG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 688-717 amino acids from the C-terminal region of human NRG3.
Clone RB2201

Target Details Neuregulin 3

Product Details anti-Neuregulin 3 Antibody Application Details Handling References for anti-Neuregulin 3 Antibody (ABIN1881587) Images back to top
Antigen
Alternative Name NRG3 (NRG3 Antibody Abstract)
Background NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization.

Synonyms: NRG3, Pro-neuregulin-3, membrane-bound isoform, Neuregulin-3
NCBI Accession NP_001159445, NP_001010848
UniProt P56975
Research Area Cancer
Pathways RTK Signaling

Application Details

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Handling References for anti-Neuregulin 3 Antibody (ABIN1881587) Images back to top
Application Notes WB: 1:1000,IHC (p): 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Application Details References for anti-Neuregulin 3 Antibody (ABIN1881587) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-Neuregulin 3 Antibody (ABIN1881587)

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Application Details Handling Images back to top
Product cited in:

Wansbury, Panchal, James, Parry, Ashworth, Howard: "Dynamic expression of Erbb pathway members during early mammary gland morphogenesis." in: The Journal of investigative dermatology, Vol. 128, Issue 4, pp. 1009-21, 2008

Zhang, Sliwkowski, Mark, Frantz, Akita, Sun, Hillan, Crowley, Brush, Godowski: "Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 18, pp. 9562-7, 1997

Images

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Application Details Handling References for anti-Neuregulin 3 Antibody (ABIN1881587) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Neuregulin 3 antibody (NRG3) (AA 688-717) (ABIN1881587) NRG3 Antibody (E703) (ABIN1881587) western blot analysis in human placenta tissue lys...
Western Blotting (WB) image for anti-Neuregulin 3 antibody (NRG3) (AA 688-717) (ABIN1881587) NRG3 Antibody (E703) (ABIN1881587) western blot analysis in human placenta tissue lys...