Neuregulin 3 antibody (AA 540-589)

Catalog No. ABIN6747092

Product Details anti-Neuregulin 3 Antibody

Target: Neuregulin 3 (NRG3)

Binding Specificity: AA 540-589

Reactivity: Human, Mouse, Rat, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human NRG3

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Rabbit (100%) Bovine, Horse, Pig, Guinea pig (92%) Chicken (91%) Dog (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa540-589 of human NRG3 (P56975-4, NP_001010848). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Rabbit (100%), Marmoset, Bovine, Bat, Horse, Pig, Opossum, Guinea pig (92%), Turkey, Zebra finch, Chicken (91%), Elephant, Dog (85%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:312500.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 50 μL sterile ddH2O.

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for Neuregulin 3

Target: Neuregulin 3 (NRG3)

Alternative Name: NRG3 (NRG3 Products)

Synonyms: NRG3 antibody, HRG3 antibody, pro-NRG3 antibody, ska antibody, RGD1559678 antibody, neuregulin 3 antibody, pro-neuregulin-3, membrane-bound isoform antibody, NRG3 antibody, nrg3 antibody, LOC100478170 antibody, Nrg3 antibody

Background: Name/Gene ID: NRG3

Synonyms: NRG3, Neuregulin-3-like polypeptide, Neuregulin 3, Pro-NRG3, HRG3

Gene ID: 10718

NCBI Accession: NP_001010848

UniProt: P56975

Pathways: RTK Signaling