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Browse our NFATC4 Proteins (NFATC4)

Full name:
Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 Proteins (NFATC4)
On www.antibodies-online.com are 4 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4) Proteins from 3 different suppliers available. Additionally we are shipping NFATC4 Antibodies (128) and NFATC4 Kits (6) and many more products for this protein. A total of 155 NFATC4 products are currently listed.
Synonyms:
3110041H08Rik, AW107667, AW546455, NF-ATc4, NFAT3, NFATC4, si:dkeyp-66d1.4
list all proteins Gene Name GeneID UniProt
NFATC4 73181 Q8K120
NFATC4 4776 Q14934
Rat NFATC4 NFATC4 305897  

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NFATC4 Proteins (NFATC4) by Origin

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More Proteins for NFATC4 Interaction Partners

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4) interaction partners

  1. Nfatc4 expression was coordinately upregulated by top hypoxia-activated transcription factors, while NFATc4 target genes were enriched in hypoxic neural stem cells.

  2. results indicate that NFAT (show NFATC1 Proteins) is a BACE1 (show BACE Proteins) transcription factor. Our study suggests that inhibition of NFAT (show NFATC1 Proteins)-mediated BACE1 (show BACE Proteins) expression may be a valuable drug target for AD therapy

  3. our results suggest that activation of NHE1 (show SLC9A1 Proteins) induces hypertrophy through the activation of NFAT3/Gata4 (show GATA4 Proteins) and OPN (show SPP1 Proteins) expression

  4. L-carnitine reversed the activation of NFAT3 and PPARa (show PPARA Proteins) caused by carboplatin through altering the phosphorylation of PTEN and AMPK (show PRKAA1 Proteins).

  5. Disrupting the calcineurin (show PPP3CA Proteins)-NFAT (show NFATC1 Proteins) axis by either genetic or pharmacologic approaches confers resistance to the development of social stress-induced voiding and dysfunction.

  6. The NFATc4-dependent increase in hippocampal neurogenesis after GABAA (show GABRg1 Proteins) receptor stimulation is required for suppression of anxiety response.

  7. IL-13 (show IL13 Proteins) specifically induced NFAT3 activation through promoting its dephosphorylation in air-liquid interface cultures of tracheal epithelial cells (mTECs).

  8. Data suggest that expression of Itpr1 (inositol 1,4,5-triphosphate receptor 1 (show ITPR1 Proteins)) in cerebral cortex neurons is regulated by dopamine D2 receptors; Itpr1 (show ITPR1 Proteins) is up-regulated via increased binding of NFATc4 and transcription factor AP-1 (show JUN Proteins) to Itpr1 (show ITPR1 Proteins) promoter.

  9. these results reveal a novel PI3K-independent role for p85alpha in controlling VEGF (show VEGFA Proteins) induction during the cellular UVB response by regulating NFAT3 activity.

  10. Over-expression of NFATc4 up-regulated collagen III, MRTF-A (a transcriptional regulator of SMA (show SMN1 Proteins)) and the NFAT (show NFATC1 Proteins)-target regulator of calcineurin (show PPP3CA Proteins) 1.4.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4) interaction partners

  1. Data indicate that RNA interference of NFAT (show NFATC1 Proteins) isoforms NFATc1 (show NFATC1 Proteins), NFATc2 (show NFAT1 Proteins), NFATc3 (show NFATC3 Proteins) and NFATc4 regulate gene expression differentially in human retinal microvascular endothelial cells (HRMEC).

  2. NFAT3 expression plays a role in regulating CXCR4 (show CXCR4 Proteins) expression.

  3. Suggest nuclear NF-AT3 and NF-AT4 (show NFATC3 Proteins) participates in atrial structural remodeling, and that PICP and TGF-beta1 (show TGFB1 Proteins) levels may be sensitive serum biomarkers to estimate atrial structural remodeling with atrial fibrillation.

  4. This is the first study to provide evidence of new and differential roles for NFAT3 and SMAD3 (show SMAD3 Proteins) in the osteoarthritis process in the regulation of miR (show MLXIP Proteins)-140 transcription

  5. Expression level of PPP3R1 (show PPP3R1 Proteins) and GATA4 (show GATA4 Proteins), and NFATC4 genes for transcription factors did not differ in studied subgroups of patients.

  6. Data indicate that NFATc3 (show NFATC3 Proteins) undergoes rapid dephosphorylation and nuclear translocation that are essentially complete within 20 min, although NFATc4 remains phosphorylated and localized to the cytosol.

  7. Syndecan-4 (show SDC4 Proteins) is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin (show PPP3CA Proteins)-NFAT (show NFATC1 Proteins) pathway

  8. Dendritic spine loss and dendritic branching simplification induced by amyloid-beta peptide exposure are mimicked by constitutively active NFATC4, and abolished when NFATC4 activation is blocked by the genetically encoded inhibitor VIVIT.

  9. Polymorphisms in the NFATc4 gene may confer certain protection or predisposition for new-onset diabetes after transplantation (NODAT).

  10. These data suggest that the opposing transcriptional activities of FoxP1 (show FOXP1 Proteins) and Nfat3 maintain cardiomyocyte homeostasis.

NFATC4 Protein Profile

Protein Summary

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with NFATC4

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (NFATC4)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (nfatc4)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (LOC100347003)
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 (Nfatc4)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (Nfatc4)
  • 3110041H08Rik protein
  • AW107667 protein
  • AW546455 protein
  • NF-ATc4 protein
  • NFAT3 protein
  • NFATC4 protein
  • si:dkeyp-66d1.4 protein

Protein level used designations for NFATC4

cytoplasmic nuclear factor of activated T-cells 4 , nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 , nuclear factor of activated T-cells, cytoplasmic 4-like , NF-AT3 , NF-ATc4 , T-cell transcription factor NFAT3 , nuclear factor of activated T-cells, cytoplasmic 4 , transcription complex subunit NF-ATc4 , T cell transcription factor NFAT3

GENE ID SPECIES
452821 Pan troglodytes
561682 Danio rerio
100054213 Equus caballus
100347003 Oryctolagus cuniculus
100385008 Callithrix jacchus
100461543 Pongo abelii
100563159 Anolis carolinensis
73181 Mus musculus
4776 Homo sapiens
480272 Canis lupus familiaris
788119 Bos taurus
305897 Rattus norvegicus
100154469 Sus scrofa
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