Browse our RAC2 Proteins (RAC2)

Full name:
Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) Proteins (RAC2)
On www.antibodies-online.com are 19 Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) Proteins from 8 different suppliers available. Additionally we are shipping RAC2 Antibodies (96) and many more products for this protein. A total of 119 RAC2 products are currently listed.
Synonyms:
AI323801, AI452260, EN-7, Gx, HSPC022, p21-Rac2, rac2
list all proteins Gene Name GeneID UniProt
RAC2 19354 Q05144
RAC2 5880 P15153
Rat RAC2 RAC2 366957  

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RAC2 Proteins (RAC2) by Origin

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Top referenced RAC2 Proteins

  1. Human RAC2 Protein expressed in Escherichia coli (E. coli) - ABIN667127 : Ambruso, Knall, Abell, Panepinto, Kurkchubasche, Thurman, Gonzalez-Aller, Hiester, deBoer, Harbeck, Oyer, Johnson, Roos: Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 references for 667127

  2. Human RAC2 Protein expressed in Escherichia coli (E. coli) - ABIN2005045 : Walmsley, Ooi, Reynolds, Smith, Ruf, Mathiot, Vanes, Williams, Cancro, Tybulewicz: Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. in Science (New York, N.Y.) 2003 (PubMed)

More Proteins for RAC2 Interaction Partners

Mouse (Murine) Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) interaction partners

  1. Rac2 to modulates the level of Rac1-dependent macrophage IL-1beta (show IL1B Proteins) expression, which consequently determines extent of atherosclerotic calcification.

  2. Rac1 and Rac2 have critical roles in skeletal metabolism.

  3. Data indicate that cytosol-to-membrane translocation of the Nox regulatory subunit p47(phox) and the small GTPase (show RACGAP1 Proteins) Rac1/2 was increased in vessels from db/db (show LEPR Proteins) mice compared with db/+ mice, an effect blunted by atorvastatin.

  4. Rac2 GTPase (show RACGAP1 Proteins) is activated downstream of alpha4beta1 integrin and the MCSF (show CSF1 Proteins) receptor to control tumor growth, metastasis and macrophage differentiation.

  5. Rac2-deficient animals have higher rates of mortality in pulmonary fibrosis.

  6. the levels of beta-catenin (show CTNNB1 Proteins) were reduced and not able to prevent the negative effect of Rac2 on PLD2 (show PLD2 Proteins) activity

  7. Data show that the Phospholipase D2 (PLD2 (show PLD2 Proteins))-GTPase (show RACGAP1 Proteins) Rac2 protein-protein interaction is sufficient for the guanine nucleotide exchange factor (show ARHGEF12 Proteins) (GEF (show ARHGEF2 Proteins)) function.

  8. Deletion of Rac1 and Rac2 in osteoclasts causes severe osteopetrosis (show CSF1 Proteins).

  9. Using Rac (show AKT1 Proteins) mutants that are defective in their ability to activate NOX2 (show CYBB Proteins), we show that Rac (show AKT1 Proteins) regulates a redox-mediated feedback loop that mediates directional migration of neutrophils.

  10. loss of either Rac1 or Rac2 is sufficient to impair survival and growth of transformed MLL (show MLL Proteins)-AF9 (show MLLT3 Proteins) leukemia

Human Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) interaction partners

  1. miR (show MLXIP Proteins)-24-1*/let-7a*-ARP2 (show ACTR2 Proteins)/3 complex-RAC (show AKT1 Proteins) isoforms pathway may represent a novel pathogenic mechanism for Hirschsprung disease.

  2. P38 MAPK (show MAPK14 Proteins), phosphorylated P38 MAPK (show MAPK14 Proteins), and RAC2 regulated in mutual feedback and negative feedback regulatory pathways, resulting in the radioresistance of G0 cells.

  3. Rac2 to modulates the level of Rac1-dependent macrophage IL-1beta (show IL1B Proteins) expression, which consequently determines extent of atherosclerotic calcification.

  4. R665W and L845F be referred to as allomorphic rather than hypermorphic mutations of PLCG2 (show PLCG2 Proteins) Rerouting of the transmembrane signals emanating from BCR (show BCR Proteins) and converging on PLCgamma2 (show PLCG2 Proteins) through Rac (show AKT1 Proteins) in ibrutinib-resistant CLL cells may provide novel drug treatment strategies to overcome ibrutinib resistance mediated by PLCG2 (show PLCG2 Proteins) mutations or to prevent its development in ibrutinib-treated CLL patients.

  5. Study showed that RhoA/Rac2 participate in hepatocellular tumorigenesis through their upregulation by AFAP1-AS1.

  6. RAC1/RAC2 and SFK are proximal and essential for phosphatidylinositol 3-kinase (PI3K (show PIK3CA Proteins)) activation in NK cell-mediated direct cytotoxicity against Cryptococcus neoformans.

  7. RAC2 specifically interacted with a set of mitochondrial proteins.

  8. our present analysis reinforces the involvement in ACT of the regulatory NADPH oxidase (show NOX1 Proteins) subunit RAC2 gene variant rs13058338 and, to a lesser extent of the CYBA (show CYBA Proteins) gene variant rs4673.

  9. homozygous loss-of-function RAC2 mutation in 2 patients with early-onset and progressive hypogammaglobulinemia(novel homozygous nonsense mutation in codon 56 (W56X)of RAC2 gene)

  10. p47(phox) and Rac2 accumulate only transiently at the phagosome at the onset of NADPH (show NQO1 Proteins) activity and detach from the phagosome before the end of reactive oxygen species production.

RAC2 Protein Profile

Protein Summary

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.

Alternative names and synonyms associated with RAC2

  • Ras-related C3 botulinum toxin substrate 2 (rac2)
  • RAS-related C3 botulinum substrate 2 (Rac2)
  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2)
  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (Rac2)
  • AI323801 protein
  • AI452260 protein
  • EN-7 protein
  • Gx protein
  • HSPC022 protein
  • p21-Rac2 protein
  • rac2 protein

Protein level used designations for RAC2

Ras-related C3 botulinum toxin substrate 2 , EN-7 protein , p21-Rac2 , protein EN-7 , ras-related C3 botulinum toxin substrate 2 , Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2) , small G protein , RAS-related C3 botulinum substrate 2 , ras-related protein

GENE ID SPECIES
100305245 Oncorhynchus mykiss
19354 Mus musculus
5880 Homo sapiens
366957 Rattus norvegicus
418044 Gallus gallus
327671 Bos taurus
100731468 Cavia porcellus
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