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Browse our RAC2 Proteins (RAC2)

Full name:
Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) Proteins (RAC2)
On www.antibodies-online.com are 21 Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) Proteins from 9 different suppliers available. Additionally we are shipping RAC2 Antibodies (94) and many more products for this protein. A total of 120 RAC2 products are currently listed.
Synonyms:
AI323801, AI452260, EN-7, Gx, HSPC022, p21-Rac2, rac2
list all proteins Gene Name GeneID UniProt
RAC2 19354 Q05144
RAC2 5880 P15153
Rat RAC2 RAC2 366957  

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RAC2 Proteins (RAC2) by Origin

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Top referenced RAC2 Proteins

  1. Human RAC2 Protein expressed in Escherichia coli (E. coli) - ABIN667127 : Ambruso, Knall, Abell, Panepinto, Kurkchubasche, Thurman, Gonzalez-Aller, Hiester, deBoer, Harbeck, Oyer, Johnson, Roos: Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 references for ABIN667127

  2. Human RAC2 Protein expressed in Escherichia coli (E. coli) - ABIN2005045 : Walmsley, Ooi, Reynolds, Smith, Ruf, Mathiot, Vanes, Williams, Cancro, Tybulewicz: Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. in Science (New York, N.Y.) 2003 (PubMed)

More Proteins for RAC2 Interaction Partners

Mouse (Murine) Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) interaction partners

  1. Data indicate that cytosol-to-membrane translocation of the Nox regulatory subunit p47(phox) and the small GTPase (show RACGAP1 Proteins) Rac1/2 was increased in vessels from db/db (show LEPR Proteins) mice compared with db/+ mice, an effect blunted by atorvastatin.

  2. Rac2 GTPase (show RACGAP1 Proteins) is activated downstream of alpha4beta1 integrin and the MCSF (show CSF1 Proteins) receptor to control tumor growth, metastasis and macrophage differentiation.

  3. Rac2-deficient animals have higher rates of mortality in pulmonary fibrosis.

  4. the levels of beta-catenin (show CTNNB1 Proteins) were reduced and not able to prevent the negative effect of Rac2 on PLD2 (show PLD2 Proteins) activity

  5. Data show that the Phospholipase D2 (PLD2 (show PLD2 Proteins))-GTPase (show RACGAP1 Proteins) Rac2 protein-protein interaction is sufficient for the guanine nucleotide exchange factor (show ARHGEF12 Proteins) (GEF (show ARHGEF2 Proteins)) function.

  6. Deletion of Rac1 and Rac2 in osteoclasts causes severe osteopetrosis (show CSF1 Proteins).

  7. Using Rac (show AKT1 Proteins) mutants that are defective in their ability to activate NOX2 (show CYBB Proteins), we show that Rac (show AKT1 Proteins) regulates a redox-mediated feedback loop that mediates directional migration of neutrophils.

  8. loss of either Rac1 or Rac2 is sufficient to impair survival and growth of transformed MLL (show MLL Proteins)-AF9 (show MLLT3 Proteins) leukemia

  9. Rac2 is essential for NET formation via pathways involving ROS (show ROS1 Proteins) and NO.

  10. We identified unique expression of asparaginyl endopeptidase (AEP (show LGMN Proteins)), intercellular adhesion molecule 1 (ICAM1 (show ICAM1 Proteins)), and ras-related C3 botulinum toxin substrate 2 (RAC2), among others, in an invasive pre-B-cell line that produced leukemia in NOD-SCID (show PRKDC Proteins) mice

Human Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2) interaction partners

  1. RAC1/RAC2 and SFK are proximal and essential for phosphatidylinositol 3-kinase (PI3K (show PIK3CA Proteins)) activation in NK cell-mediated direct cytotoxicity against Cryptococcus neoformans.

  2. RAC2 specifically interacted with a set of mitochondrial proteins.

  3. our present analysis reinforces the involvement in ACT of the regulatory NADPH oxidase (show NOX1 Proteins) subunit RAC2 gene variant rs13058338 and, to a lesser extent of the CYBA (show CYBA Proteins) gene variant rs4673.

  4. homozygous loss-of-function RAC2 mutation in 2 patients with early-onset and progressive hypogammaglobulinemia(novel homozygous nonsense mutation in codon 56 (W56X)of RAC2 gene)

  5. p47(phox) and Rac2 accumulate only transiently at the phagosome at the onset of NADPH (show NQO1 Proteins) activity and detach from the phagosome before the end of reactive oxygen species production.

  6. These studies imply functional importance of iNOS (show NOS2 Proteins) and its interaction with Rac2 in pathogen killing by the neutrophils.

  7. findings indicate that a chemokine-controlled pathway, consisting of Galphai2, ELMO1/Dock180, Rac1 and Rac2, regulates the actin cytoskeleton during breast cancer metastasis

  8. Mutations in hematopoiesis-specific Rho GTPases Rac2 and RhoH lead to a wide range of human blood disorders. (Review)

  9. study identified several missense mutations for RAC1 and RAC2, with some of the mutant proteins, including RAC1(P29S), RAC1(C157Y), RAC2(P29L), and RAC2(P29Q), being found to be activated and transforming; activating mutations of RAC (show AKT1 Proteins) GTPases were thus found in a wide variety of cancers at a low frequency

  10. This variant reduced binding of the NCF2 (show NCF2 Proteins) gene product p67(phox (show NCF2 Proteins)) to RAC2. This study found a novel genetic association of RAC2 with Crohn's disease (CD) and replicated the previously reported association of NCF4 (show NCF4 Proteins) with ileal CD.

RAC2 Protein Profile

Protein Summary

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.

Alternative names and synonyms associated with RAC2

  • Ras-related C3 botulinum toxin substrate 2 (rac2)
  • RAS-related C3 botulinum substrate 2 (Rac2)
  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2)
  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (Rac2)
  • AI323801 protein
  • AI452260 protein
  • EN-7 protein
  • Gx protein
  • HSPC022 protein
  • p21-Rac2 protein
  • rac2 protein

Protein level used designations for RAC2

Ras-related C3 botulinum toxin substrate 2 , EN-7 protein , p21-Rac2 , protein EN-7 , ras-related C3 botulinum toxin substrate 2 , Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2) , small G protein , RAS-related C3 botulinum substrate 2 , ras-related protein

GENE ID SPECIES
100305245 Oncorhynchus mykiss
19354 Mus musculus
5880 Homo sapiens
366957 Rattus norvegicus
418044 Gallus gallus
327671 Bos taurus
100731468 Cavia porcellus
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