anti-Human TSC1 antibody for Immunofluorescence

Recommended TSC1 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 1 (TSC1) Antibodies
  • tsc1
  • wu:fc38b04
  • LAM
  • TSC
  • hamartin
  • mKIAA0243
  • tuberous sclerosis 1
  • tuberous sclerosis 1b
  • TSC1
  • tsc1b
  • tsc1
  • Tsc1
Epitope
AA 401-430
50
40
40
40
40
30
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
16
12
12
10
9
7
7
7
5
5
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
462
379
172
28
7
6
5
1
1
Host
Rabbit
742
57
19
2
Clonality
Polyclonal
Conjugate
This TSC1 antibody is un-conjugated
67
67
67
64
64
64
5
5
5
5
5
3
3
3
3
3
3
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
532
517
165
65
39
34
27
21
16
8
4
2
1
Supplier
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Catalog No. ABIN3029277
$ 411.13
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.326117 ABIN5080330 ICC IF Rabbit IgG Log in to see Polyclonal
1 ABIN652207 IF IHC (p) WB Rabbit Ig AA 401-430, Center Log in to see Polyclonal 2
1 ABIN303311 IF IHC (p) WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN5555392 EIA IF WB Rabbit IgG Middle Region, both Isoforms Log in to see Polyclonal
1 ABIN2650961 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN121908 IF WB Rabbit Log in to see Polyclonal 2
1 ABIN320501 IF WB Rabbit IgG Log in to see Polyclonal
1 ABIN1900970 ELISA ICC IF IHC WB Alkaline Phosphatase (AP) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1900972 ELISA ICC IF IHC WB FITC Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1900973 ELISA ICC IF IHC WB Biotin Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1900974 ELISA ICC IF IHC WB PE Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1900971 ELISA ICC IF IHC WB APC Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1900969 ELISA ICC IF IHC WB HRP Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN2605251 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN2278826 IF IHC ELISA WB Rabbit IgG Center, Internal Region Log in to see Polyclonal
1 ABIN2278830 IF IHC ELISA WB APC Rabbit IgG Center, Internal Region Log in to see Polyclonal
1 ABIN2278825 IF IHC ELISA WB PE Rabbit IgG Center, Internal Region Log in to see Polyclonal
1 ABIN2278832 IF IHC ELISA WB FITC Rabbit IgG Center, Internal Region Log in to see Polyclonal
1 ABIN4363048 ELISA ICC IF WB Rabbit all Isoforms Log in to see Polyclonal
1 ABIN4363049 ELISA ICC IF WB Rabbit all Isoforms Log in to see Polyclonal

Similar anti-TSC1 Antibodies

Application / Reactivity Human
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ELISA 258 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 20 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 28 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 39 Antibodies
Immunohistochemistry (IHC) 66 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 34 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 150 Antibodies

General

Antigen Tuberous Sclerosis 1 (TSC1) Antibodies
Epitope AA 401-430
(50), (40), (40), (40), (40), (30), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (16), (12), (12), (10), (9), (7), (7), (7), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(462), (379), (172), (28), (7), (6), (5), (1), (1)
Host Rabbit
(742), (57), (19), (2)
Clonality
Polyclonal
Conjugate This TSC1 antibody is un-conjugated
(67), (67), (67), (64), (64), (64), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(532), (517), (165), (65), (39), (34), (27), (21), (16), (8), (4), (2), (1)
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Product Details anti-TSC1 Antibody

Target Details TSC1 Application Details Handling Images
Purification Antigen affinity purified
Immunogen A portion of amino acids 401-430 from the human protein was used as the immunogen for this Hamartin antibody.
Isotype Ig Fraction

Target Details TSC1

Product Details anti-TSC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Hamartin (TSC1 Antibody Abstract)
Background Implicated as a tumor suppressor. May have a function in vesicular transport. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Defects in TSC1 are the cause of tuberous sclerosis complex (TSC). The molecular basis of TSC is a functional impairement of the hamartin-tuberin complex. TSC is an autosomal dominant multi-system disorder that affects especially the brain, kidneys, heart, and skin. TSC is characterized by hamartomas (benign overgrowths predominantly of a cell or tissue type that occurs normally in the organ) and hamartias (developmental abnormalities of tissue combination). Clinical symptoms can range from benign hypopigmented macules of the skin to profound mental retardation with intractable seizures to premature death from a variety of disease-associated causes. Defects in TSC1 may be a cause of focal cortical dysplasia of Taylor balloon cell type (FCDBC). FCDBC is a subtype of cortical displasias linked to chronic intractable epilepsy. Cortical dysplasias display a broad spectrum of structural changes, which appear to result from changes in proliferation, migration, differentiation, and apoptosis of neuronal precursors and neurons during cortical development.
UniProt Q92574
Research Area Cancer, Cell Cycle, Transcription Factors
Pathways RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation

Application Details

Product Details anti-TSC1 Antibody Target Details TSC1 Handling Images back to top
Application Notes Titration of the Hamartin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Restrictions For Research Use only

Handling

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Images back to top
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the Hamartin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-TSC1 antibody (Tuberous Sclerosis 1) (AA 401-430) (ABIN3029277) Confocal immunofluorescent analysis of Hamartin antibody with HeLa cells followed by ...
Immunohistochemistry (IHC) image for anti-TSC1 antibody (Tuberous Sclerosis 1) (AA 401-430) (ABIN3029277) Hamartin antibody immunohistochemistry analysis in formalin fixed and paraffin embedd...
Western Blotting (WB) image for anti-TSC1 antibody (Tuberous Sclerosis 1) (AA 401-430) (ABIN3029277) Hamartin antibody western blot analysis in MDA-MB231 lysate